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Plant extract may be new therapy for hay fever, study suggests

Date:
April 30, 2011
Source:
Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health
Summary:
Fighting hay fever with a plant extract? It works, as was shown in a new clinical study. Allergic symptoms were alleviated significantly better than with the usual histamine receptor antagonists.

Electron micrograph of birch pollen.
Credit: Dr. Ingrid Weichenmeier, ZAUM

Fighting hay fever with a plant extract -- this works, as was shown in a clinical study conducted by researchers of the Center of Allergy & Environment (ZAUM) of Helmholtz Zentrum München and Technische Universität München. Allergic symptoms were alleviated significantly better than with the usual histamine receptor antagonists. In a paper published in the Journal of Allergy and Clinical Immunology the scientists explained how this plant extract works and how effective it is.

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Antihistamine medications have long been considered the treatment of choice to alleviate the symptoms of hay fever sufferers. Now, in a randomized double-blind study, Dr. Adam Chaker and Prof. Dr. Carsten Schmidt-Weber demonstrated that the plant extract Ze 339 (Petasol butenoate complex) combats nasal mucosa swelling faster and more effectively.

Apparently, however, the extract not only works in acute cases -- "Our data indicate that the extract also has a preventive effect, which must be investigated further," said Dr. Schmidt-Weber, head of the Center of Allergy & Environment (ZAUM) in Munich. The results look promising for improving the quality of life of people with allergies.

So far the plant extract has only been approved as a drug in Switzerland and South Korea. Further studies need to be carried out in order to allow it to be sold as a prescription drug elsewhere.


Story Source:

The above story is based on materials provided by Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health. Note: Materials may be edited for content and length.


Journal Reference:

  1. Alina F. Dumitru, Mohamed Shamji, Martin Wagenmann, Simone Hindersin, Kathrin Scheckenbach, Jens Greve, Thomas Klenzner, Lorenzo Hess, Sabine Nebel, Christian Zimmermann, Catherine Zahner, Carsten B. Schmidt-Weber, Adam M. Chaker. Petasol butenoate complex (Ze 339) relieves allergic rhinitis–induced nasal obstruction more effectively than desloratadine. Journal of Allergy and Clinical Immunology, 2011; DOI: 10.1016/j.jaci.2011.02.045

Cite This Page:

Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health. "Plant extract may be new therapy for hay fever, study suggests." ScienceDaily. ScienceDaily, 30 April 2011. <www.sciencedaily.com/releases/2011/04/110427070904.htm>.
Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health. (2011, April 30). Plant extract may be new therapy for hay fever, study suggests. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2011/04/110427070904.htm
Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health. "Plant extract may be new therapy for hay fever, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/04/110427070904.htm (accessed October 31, 2014).

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