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Plant Extract May Be New Therapy for Hay Fever, Study Suggests

Apr. 30, 2011 — Fighting hay fever with a plant extract -- this works, as was shown in a clinical study conducted by researchers of the Center of Allergy & Environment (ZAUM) of Helmholtz Zentrum München and Technische Universität München. Allergic symptoms were alleviated significantly better than with the usual histamine receptor antagonists. In a paper published in the Journal of Allergy and Clinical Immunology the scientists explained how this plant extract works and how effective it is.


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Antihistamine medications have long been considered the treatment of choice to alleviate the symptoms of hay fever sufferers. Now, in a randomized double-blind study, Dr. Adam Chaker and Prof. Dr. Carsten Schmidt-Weber demonstrated that the plant extract Ze 339 (Petasol butenoate complex) combats nasal mucosa swelling faster and more effectively.

Apparently, however, the extract not only works in acute cases -- "Our data indicate that the extract also has a preventive effect, which must be investigated further," said Dr. Schmidt-Weber, head of the Center of Allergy & Environment (ZAUM) in Munich. The results look promising for improving the quality of life of people with allergies.

So far the plant extract has only been approved as a drug in Switzerland and South Korea. Further studies need to be carried out in order to allow it to be sold as a prescription drug elsewhere.

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The above story is reprinted from materials provided by Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Alina F. Dumitru, Mohamed Shamji, Martin Wagenmann, Simone Hindersin, Kathrin Scheckenbach, Jens Greve, Thomas Klenzner, Lorenzo Hess, Sabine Nebel, Christian Zimmermann, Catherine Zahner, Carsten B. Schmidt-Weber, Adam M. Chaker. Petasol butenoate complex (Ze 339) relieves allergic rhinitis–induced nasal obstruction more effectively than desloratadine. Journal of Allergy and Clinical Immunology, 2011; DOI: 10.1016/j.jaci.2011.02.045
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