Featured Research

from universities, journals, and other organizations

CPAP improves daytime sleepiness even in patients with low levels of symptoms

Date:
May 15, 2011
Source:
American Thoracic Society
Summary:
Continuous positive airway pressure, or CPAP, can increase alertness and even improve quality of life for sufferers of obstructive sleep apnea (OSA), even if their symptoms are minimal, according to a new study conducted by researchers in Europe. Patients enrolled in the study reported an improvement in daytime sleepiness within six months of beginning CPAP treatment.

Continuous positive airway pressure, or CPAP, can increase alertness and even improve quality of life for sufferers of obstructive sleep apnea (OSA), even if their symptoms are minimal, according to a study conducted by researchers in Europe. Patients enrolled in the study reported an improvement in daytime sleepiness within six months of beginning CPAP treatment.

Related Articles


The study was presented at the ATS 2011 International Conference in Denver.

"Treatment with CPAP clearly reduces daytime sleepiness and improves quality of life in patients with very limited symptoms, at a rate of about half the improvement seen in patients with more severe symptoms," said Sonya Craig, research fellow at Churchill Hospital, Oxford.

"It is well-known that CPAP treatment greatly improves OSA patients who have substantial symptoms of daytime sleepiness," she added. "However, OSA with few symptoms, and sometimes no symptoms, is much more common, yet the effect of CPAP on these patients has not been adequately evaluated. In this study, we wanted to investigate the effect of CPAP on sleepiness and quality of life measurements in patients with minimally symptomatic OSA."

Researchers analyzed data from 341 patients from 10 medical centers, with proven OSA but insufficient current symptoms as judged by both the patient and the sleep physician to justify CPAP therapy. Patients were randomized to receive either six months of CPAP or no treatment. The Epworth Sleepiness Score, a standard scoring system used in sleep studies, was used to determine the change in daytime sleepiness measured at the start of the study, and again at follow-up six months later. Wakefulness and sleepiness were also measured using a second test, called the Oxford Sleep Resistance Test (OSLER), and quality of life was assessed using a standard questionnaire.

The researchers found that after six months of treatment, CPAP significantly reduced daytime sleepiness and increased wakefulness compared to the standard treatment group. They also found that the odds of falling asleep during the OSLER test, which requires patients to lie quietly and react to a flashing light for prolonged periods of time at repeated intervals, were 49 percent lower in the CPAP treatment group compared to those in the standard care group. Quality of life scores were also significantly higher in the CPAP group compared to standard care patients. Ironically, about 25 percent of patients stopped treatment prior to the end of the study, reporting that they did not perceive adequate benefit.

Dr. Craig said the results of the study were surprising.

"The magnitude of the improvement in sleepiness and quality of life scores wasgreater than expected, particularly given that the patients were considered to have only very mild symptoms when assessed in clinic," she said.

"It appears clinical assessment of patients with OSA does not reliably identify all patients likely to benefit from treatment with CPAP," she added. "This suggests that a greater number of patients than originally thought may benefit from a trial of CPAP therapy."

Dr. Craig said further evaluation will focus on determining if the improvements noted in the study are short-term improvement, or if they are long-lasting.

"We are continuing to follow these patients for a longer term to assess whether the improvements in quality of life and daytime symptoms are maintained over a longer time scale," she said. "If the benefits persist for a longer time period, it would strengthen the argument to expand the patient population that could benefit significantly from CPAP therapy."


Story Source:

The above story is based on materials provided by American Thoracic Society. Note: Materials may be edited for content and length.


Cite This Page:

American Thoracic Society. "CPAP improves daytime sleepiness even in patients with low levels of symptoms." ScienceDaily. ScienceDaily, 15 May 2011. <www.sciencedaily.com/releases/2011/05/110515122452.htm>.
American Thoracic Society. (2011, May 15). CPAP improves daytime sleepiness even in patients with low levels of symptoms. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2011/05/110515122452.htm
American Thoracic Society. "CPAP improves daytime sleepiness even in patients with low levels of symptoms." ScienceDaily. www.sciencedaily.com/releases/2011/05/110515122452.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins