Featured Research

from universities, journals, and other organizations

New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel

Date:
June 13, 2011
Source:
IOS Press
Summary:
In a new study, Israeli researchers report that by tracking pharmacy purchases of anti-Parkinson drugs they could estimate the number of Parkinson's disease (PD) cases in a large population. The study identified a sharp rise in PD prevalence from 170/100,000 in 2000 to 256/100,000 in 2007 in Israel, which warrants further investigation.

In a new study published in the inaugural issue of the Journal of Parkinson's Disease, Israeli researchers report that by tracking pharmacy purchases of anti-Parkinson drugs they could estimate the number of Parkinson's disease (PD) cases in a large population. The study identified a sharp rise in PD prevalence from 170/100,000 in 2000 to 256/100,000 in 2007 in Israel, which warrants further investigation.

Surprisingly, much of the world lacks accurate figures for the percentage of the population (prevalence) with PD and the rate of occurrence of new cases (incidence). Reliable estimates using "epidemiological" population studies are essential to identify risk factors for developing the disease, and thereby reduce risk. They are also essential for planning how many patients with the disease may need treatment by health services.

"Our proposed algorithm may be used as a reliable and low-cost tool to establish PD cohorts for epidemiological studies," commented lead investigator Nir Giladi, MD, Chairman, Department of Neurology, Tel Aviv Sourasky Medical Center, and Associate Professor, Sackler School of Medicine, Tel Aviv University. "Our findings of prevalence and incidence are higher than expected, and a rising number of PD patients in Israel reflect the growing burden of PD morbidity on Israeli health and social systems, and should be the base for national resource planning for the future."

The refined drug-driven algorithm used assessed PD patients at three certainty levels -- definite, probable, and possible -- based on the fact that PD therapy is chronic and generally involves an increasing number of drug-types and dosages as the disease progresses. Thus, those levels of accuracy were assigned based on specific combinations of categories of four factors: (a) PD drug types used; (b) age at first PD drug purchase (c) follow-up period; and (d) PD drug purchase intensity -- number and continuity of purchases.

Using the pharmacy records of over 1.8 million people who were members of the Maccabi Healthcare Service (MHS) in Israel (about 25% of the total population), researchers found 499,629 PD drug prescriptions were dispensed to 18,546 MHS members between January 1, 1998 and December 31, 2008. The algorithm identified 7,134 PD cases overall and 5,288 new cases within this timeframe. Annual prevalence rates increased from 170/100,000 in 2000 to 256/100,000 in 2007, or 6% per year.


Story Source:

The above story is based on materials provided by IOS Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Orly Chillag-Talmor, Nir Giladi, Shai Linn, Tanya Gurevich, Baruch El-Ad, Barbara Silverman, Nurit Friedman, and Chava Peretz. Use of a refined drug tracer algorithm to estimate prevalence and incidence of Parkinson's disease in a large Israeli population. Journal of Parkinson's Disease, 2011; 1 (1) DOI: 10.3233/JPD-2011-11024

Cite This Page:

IOS Press. "New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel." ScienceDaily. ScienceDaily, 13 June 2011. <www.sciencedaily.com/releases/2011/06/110609123338.htm>.
IOS Press. (2011, June 13). New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2011/06/110609123338.htm
IOS Press. "New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel." ScienceDaily. www.sciencedaily.com/releases/2011/06/110609123338.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins