Featured Research

from universities, journals, and other organizations

New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel

Date:
June 13, 2011
Source:
IOS Press
Summary:
In a new study, Israeli researchers report that by tracking pharmacy purchases of anti-Parkinson drugs they could estimate the number of Parkinson's disease (PD) cases in a large population. The study identified a sharp rise in PD prevalence from 170/100,000 in 2000 to 256/100,000 in 2007 in Israel, which warrants further investigation.

In a new study published in the inaugural issue of the Journal of Parkinson's Disease, Israeli researchers report that by tracking pharmacy purchases of anti-Parkinson drugs they could estimate the number of Parkinson's disease (PD) cases in a large population. The study identified a sharp rise in PD prevalence from 170/100,000 in 2000 to 256/100,000 in 2007 in Israel, which warrants further investigation.

Surprisingly, much of the world lacks accurate figures for the percentage of the population (prevalence) with PD and the rate of occurrence of new cases (incidence). Reliable estimates using "epidemiological" population studies are essential to identify risk factors for developing the disease, and thereby reduce risk. They are also essential for planning how many patients with the disease may need treatment by health services.

"Our proposed algorithm may be used as a reliable and low-cost tool to establish PD cohorts for epidemiological studies," commented lead investigator Nir Giladi, MD, Chairman, Department of Neurology, Tel Aviv Sourasky Medical Center, and Associate Professor, Sackler School of Medicine, Tel Aviv University. "Our findings of prevalence and incidence are higher than expected, and a rising number of PD patients in Israel reflect the growing burden of PD morbidity on Israeli health and social systems, and should be the base for national resource planning for the future."

The refined drug-driven algorithm used assessed PD patients at three certainty levels -- definite, probable, and possible -- based on the fact that PD therapy is chronic and generally involves an increasing number of drug-types and dosages as the disease progresses. Thus, those levels of accuracy were assigned based on specific combinations of categories of four factors: (a) PD drug types used; (b) age at first PD drug purchase (c) follow-up period; and (d) PD drug purchase intensity -- number and continuity of purchases.

Using the pharmacy records of over 1.8 million people who were members of the Maccabi Healthcare Service (MHS) in Israel (about 25% of the total population), researchers found 499,629 PD drug prescriptions were dispensed to 18,546 MHS members between January 1, 1998 and December 31, 2008. The algorithm identified 7,134 PD cases overall and 5,288 new cases within this timeframe. Annual prevalence rates increased from 170/100,000 in 2000 to 256/100,000 in 2007, or 6% per year.


Story Source:

The above story is based on materials provided by IOS Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Orly Chillag-Talmor, Nir Giladi, Shai Linn, Tanya Gurevich, Baruch El-Ad, Barbara Silverman, Nurit Friedman, and Chava Peretz. Use of a refined drug tracer algorithm to estimate prevalence and incidence of Parkinson's disease in a large Israeli population. Journal of Parkinson's Disease, 2011; 1 (1) DOI: 10.3233/JPD-2011-11024

Cite This Page:

IOS Press. "New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel." ScienceDaily. ScienceDaily, 13 June 2011. <www.sciencedaily.com/releases/2011/06/110609123338.htm>.
IOS Press. (2011, June 13). New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2011/06/110609123338.htm
IOS Press. "New method for measuring Parkinson's disease prevalence reveals sharp increase in Israel." ScienceDaily. www.sciencedaily.com/releases/2011/06/110609123338.htm (accessed April 21, 2014).

Share This



More Health & Medicine News

Monday, April 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins