Featured Research

from universities, journals, and other organizations

Using living cells as an 'invisibility cloak' to hide drugs

Date:
June 16, 2011
Source:
American Chemical Society
Summary:
The quest for better ways of encapsulating medicine so that it can reach diseased parts of the body has led scientists to harness -- for the first time -- living human cells to produce natural capsules with channels for releasing drugs and diagnostic agents.

The quest for better ways of encapsulating medicine so that it can reach diseased parts of the body has led scientists to harness -- for the first time -- living human cells to produce natural capsules with channels for releasing drugs and diagnostic agents. The report appears in ACS' journal Nano Letters.

In the report, Dayang Wang and colleagues explain that the human body is very efficient at getting rid of foreign substances. Some foreign substances, such as viruses, are harmful and should be removed. But the body also considers drugs and nanoparticles -- meant to treat diseases and allow physicians to see cells and organs -- to be foreign objects, and they are also quickly removed. To help these substances stay in the body longer, scientists have tried to fool it by encapsulating these substances in coatings that more closely resemble natural cells. Over the years, researchers have tested many different artificial coatings, but they failed to stay in the body for very long. So, Wang and colleagues set out to make a better capsule -- by using living cells as an "invisibility cloak."

Because the group's so-called "cell membrane capsules" (CMCs) were made from real living cells, they tricked the body into thinking they were supposed to be there. Thus, drugs and nanoparticles inside CMCs stayed in the body much longer than those inside other encapsulation materials. "Hence the CMCs provide the first intrinsically biocompatible and functional drug delivery and release vehicles," say the researchers.

The authors acknowledge funding from the Max Planck Society and Deutsche Forschungsgemeinschaft.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Zhengwei Mao, Regis Cartier, Anja Hohl, Maura Farinacci, Anca Dorhoi, Tich-Lam Nguyen, Paul Mulvaney, John Ralston, Stefan H. E. Kaufmann, Helmuth Möhwald, Dayang Wang. Cells as Factories for Humanized Encapsulation. Nano Letters, 2011; 110412134243000 DOI: 10.1021/nl200801n

Cite This Page:

American Chemical Society. "Using living cells as an 'invisibility cloak' to hide drugs." ScienceDaily. ScienceDaily, 16 June 2011. <www.sciencedaily.com/releases/2011/06/110615103046.htm>.
American Chemical Society. (2011, June 16). Using living cells as an 'invisibility cloak' to hide drugs. ScienceDaily. Retrieved August 2, 2014 from www.sciencedaily.com/releases/2011/06/110615103046.htm
American Chemical Society. "Using living cells as an 'invisibility cloak' to hide drugs." ScienceDaily. www.sciencedaily.com/releases/2011/06/110615103046.htm (accessed August 2, 2014).

Share This




More Health & Medicine News

Saturday, August 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Quintuplets Head Home

Texas Quintuplets Head Home

Reuters - US Online Video (Aug. 1, 2014) After four months in the hospital, the first quintuplets to be born at Baylor University Medical Center head home. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Patient Coming to U.S. for Treatment

Ebola Patient Coming to U.S. for Treatment

Reuters - US Online Video (Aug. 1, 2014) A U.S. aid worker infected with Ebola while working in West Africa will be treated in a high security ward at Emory University in Atlanta. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Ebola Vaccine Might Be Coming, But Where's It Been?

Ebola Vaccine Might Be Coming, But Where's It Been?

Newsy (Aug. 1, 2014) Health officials are working to fast-track a vaccine — the West-African Ebola outbreak has killed more than 700. But why didn't we already have one? Video provided by Newsy
Powered by NewsLook.com
Study Links Certain Birth Control Pills To Breast Cancer

Study Links Certain Birth Control Pills To Breast Cancer

Newsy (Aug. 1, 2014) Previous studies have made the link between birth control and breast cancer, but the latest makes the link to high-estrogen oral contraceptives. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins