Featured Research

from universities, journals, and other organizations

Worse outcomes for older breast cancer patients with other health problems, study finds

Date:
June 30, 2011
Source:
Journal of the National Cancer Institute
Summary:
Older breast cancer patients with certain other health problems have higher mortality rates than patients without these problems, according to a new study. The other health problems, or "comorbidities," include heart attack and other heart-related problems, chronic obstructive pulmonary disease, diabetes and others.

Older breast cancer patients with certain other health problems have higher mortality rates than patients without these problems according to a study published online June 30 in the Journal of the National Cancer Institute. The other health problems, or 'comorbidities', include heart attack and other heart-related problems, chronic obstructive pulmonary disease, diabetes, and others.

Previous studies have shown that comorbidities as a group are associated with poorer overall survival and higher overall death rates among breast cancer patients. In this study, Jennifer L. Patnaik, Ph.D., of the University of Colorado Denver, Aurora, and colleagues looked at the association between each of 13 individual conditions and survival.

Using the Surveillance, Epidemiology, and End Results-Medicare database, the researchers identified 64,034 women age 66 years and older who were diagnosed with breast cancer between 1992 and 2000. Of these, 42% had a history of one or more of 13 conditions -- stroke, chronic obstructive pulmonary disease, chronic renal failure, congestive heart failure, dementia, diabetes, liver disease, heart attack, paralysis, peripheral vascular disease, previous cancer, rheumatoid arthritis, and ulcers.

Each of these conditions was independently associated with increased overall mortality (deaths from any cause including cancer) and lower overall survival rates. When the researchers looked at each comorbid condition in patients age 66-74, they found that patients with stage 1 tumors and the comorbidity had overall survival rates the same as or worse than patients with stage II tumors and no comorbidities.

The authors conclude that comorbidities are important in predicting survival of breast cancer patients. They write that the study suggests that "careful attention to the effective management of comorbid conditions, as well as to the management of a patient's cancer, may result in longer overall survival for older breast cancer patients."

In an accompanying editorial, Worta McCaskill-Stevens, M.D., and Jeff Abrams, M.D., of the National Cancer Institute, Bethesda, Md., discuss the importance of studying older breast cancer patients, who account for a large proportion of women with the disease and who often have comorbidities. They conclude that the findings of this study "are provocative, suggesting that care should be individualized in patients with comorbidities and the diseases should be co-managed between oncologists and primary care physicians."


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jennifer L. Patnaik, Tim Byers, Carolyn Diguiseppi, Thomas D. Denberg, Dana Dabelea. The Influence of Comorbidities on Overall Survival Among Older Women Diagnosed With Breast Cancer. Journal of the National Cancer Institute, 2011; DOI: 10.1093/jnci/djr188

Cite This Page:

Journal of the National Cancer Institute. "Worse outcomes for older breast cancer patients with other health problems, study finds." ScienceDaily. ScienceDaily, 30 June 2011. <www.sciencedaily.com/releases/2011/06/110630161832.htm>.
Journal of the National Cancer Institute. (2011, June 30). Worse outcomes for older breast cancer patients with other health problems, study finds. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2011/06/110630161832.htm
Journal of the National Cancer Institute. "Worse outcomes for older breast cancer patients with other health problems, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/06/110630161832.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
'Cadaver Dog' Sniffs out Human Remains

'Cadaver Dog' Sniffs out Human Remains

AP (Oct. 21, 2014) Where's a body buried? Buster's nose can often tell you. He's a cadaver dog, specially trained to find human remains and increasingly being used by law enforcement and accepted in courts. These dogs are helping solve even decades-old mysteries. (Oct. 21) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins