Featured Research

from universities, journals, and other organizations

Arthritis sufferers' increased risk of heart disease due to disease-related inflammation and other factors, study finds

Date:
August 15, 2011
Source:
BioMed Central
Summary:
Rheumatoid arthritis (RA) sufferers are at an increased risk of dying due to cardiovascular disease. A new five-year study showed that the risk of cardiovascular disease for people with RA is due to disease-related inflammation as well as the risk factors which affect the general population. Treatment of arthritis with disease modifying anti-rheumatic drugs also reduced the patient's risk of heart disease.

Rheumatoid arthritis (RA) sufferers are at an increased risk of dying due to cardiovascular disease. A new five year study published in BioMed Central's open access journal Arthritis Research & Therapy showed that the risk of cardiovascular disease for people with RA is due to disease-related inflammation as well as the risk factors which affect the general population. Treatment of arthritis with disease modifying antirheumatic drugs (DMARDs) also reduced the patient's risk of heart disease.

Over 400 people with RA were followed from date of diagnosis for five years. Progression of their disease was measured using chemical markers of inflammation and physical appearance. Treatment regimes were monitored along with risk factors for heart disease, including weight, cholesterol levels, blood pressure, diabetes and smoking.

After five years, 97% of the patients had been treated with DMARDs, reducing both the chemical markers of inflammation and the physical appearance of their arthritis. Patients were also looking after themselves better -- fewer patients were smokers and their BMI, and blood pressure, had reduced (due in part to treatment for high blood pressure).

Analysis of the patient data revealed that a new cardiovascular event such as heart disease, stroke or DVT could be predicted by intensity of their arthritis and by presence of diabetes, high blood pressure, and the level of triglycerides. Encouragingly treatment with DMARDs decreased the risk but COX-2 inhibitors appeared to predict a new event.

Dr Wållberg-Jonsson from University Hospital, Umeå, in Sweden said, "Inflammation associated with rheumatoid arthritis increases patients risk of heart disease and other cardiovascular events. However it is possible to reduce this risk in a two-pronged attack by treating both the inflammation and traditional risk factors for heart disease."


Story Source:

The above story is based on materials provided by BioMed Central. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lena Innala, Bozena Möller, Lotta Ljung, Staffan Magnusson, Torgny Smedby, Anna Södergren, Marie-Louise Öhman, Solbritt Rantapää-Dahlqvist and Solveig Wållberg-Jonsson. Cardiovascular events in early rheumatoid arthritis (RA) are a result of inflammatory burden and traditional risk factors: a five year prospective study. Arthritis Research & Therapy, 2011 [link]

Cite This Page:

BioMed Central. "Arthritis sufferers' increased risk of heart disease due to disease-related inflammation and other factors, study finds." ScienceDaily. ScienceDaily, 15 August 2011. <www.sciencedaily.com/releases/2011/08/110814223811.htm>.
BioMed Central. (2011, August 15). Arthritis sufferers' increased risk of heart disease due to disease-related inflammation and other factors, study finds. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2011/08/110814223811.htm
BioMed Central. "Arthritis sufferers' increased risk of heart disease due to disease-related inflammation and other factors, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/08/110814223811.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) — Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com
Condemned Man's US Execution Takes Nearly Two Hours

Condemned Man's US Execution Takes Nearly Two Hours

AFP (July 24, 2014) — America's death penalty debate raged Thursday after it took nearly two hours for Arizona to execute a prisoner who lost a Supreme Court battle challenging the experimental lethal drug cocktail. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
China's Ageing Millions Look Forward to Bleak Future

China's Ageing Millions Look Forward to Bleak Future

AFP (July 24, 2014) — China's elderly population is expanding so quickly that children struggle to look after them, pushing them to do something unexpected in Chinese society- move their parents into a nursing home. Duration: 02:07 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins