Featured Research

from universities, journals, and other organizations

Deadly ancient Egyptian medication? German scientists shed light on dark secret of Queen Hatshepsut's flacon

Date:
August 22, 2011
Source:
University of Bonn
Summary:
The corpus delicti is a plain flacon from among the possessions of Pharaoh Hatshepsut, who lived around 1450 B.C., which is on exhibit in the permanent collection of the Egyptian Museum of the University of Bonn in Germany. For three and a half millennia, the vessel may have held a deadly secret. This is what researchers there have just discovered.

Michael Höveler-Müller (left) and Dr. Helmut Wiedenfeld with the mysterious vial.
Credit: Barbara Frommann / Uni Bonn

The corpus delicti is a plain flacon from among the possessions of Pharaoh Hatshepsut, who lived around 1450 B.C., which is on exhibit in the permanent collection of the Egyptian Museum of the University of Bonn. For three and a half millennia, the vessel may have held a deadly secret. This is what the Head of the collection, Michael Höveler-Müller and Dr. Helmut Wiedenfeld from the university's Pharmacology Institute just discovered.

After two years of research it is now clear that the flacon did not hold a perfume; instead, it was a kind of skin care lotion or even medication for a monarch suffering from eczema. In addition, the pharmacologists found a strongly carcinogenic substance. Was Hatshepsut killed by her medicine?

When Michael Höveler-Müller became the curator of the Egyptian Museum of the University of Bonn in 2009, it occurred to him to examine the interior of the vessel that, according to an inscription, belonged to Pharaoh Hatshepsut. Its neck had been blocked with what was generally considered "dirt," but Höveler-Müller suspected that it might also be the original clay stopper. So possibly, some of the original contents might still be inside. In Dr. Helmut Wiedenfeld from the Pharmacy Institute, he found just the right partner, to get to the bottom of this question and of the flacon.

At the Radiology Clinic of the Bonn Universitätsklinikum, the flacon was subjected to a CAT scan. Here, the Egyptologist's suspicion was confirmed -- not only was the closure intact, but the vessel also held residue of a dried-up liquid. In the summer of 2009, Professor Dr. Friedrich Bootz from the Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde (laryngology, rhinology and otology) of the University of Bonn took samples, using an endoscope.

Too greasy for perfume

This allowed Dr. Wiedenfeld and his team to analyze the old substances for their ingredients. And it became obvious very quickly that what they had found was not dried-up perfume. The mix contained large amounts of palm oil and nutmeg apple oil. "I didn't think anybody would put so much grease on her face," said Dr. Wiedenfeld. "That would make her look as greasy as a plate of ribs." Two additional components clued the pharmacologist in to the actual purpose of the mix, "We found a lot of unsaturated fatty acids that provide relief for people with skin diseases." And this is where the Egyptologist was able to add another piece of the puzzle, "It is indeed known that there were cases of skin disease in Hatshepsut's family." Inflammatory skin diseases such as psoriasis have a largely genetic component.

And the third group of ingredients also points to the fact that this substance was not about providing a nice fragrance, but instead, for fighting a big itch -- the pharmacologists found a lot of hydrocarbons derived from creosote and asphalt. To this day, creams containing creosote are used to treat chronic skin diseases. Due to the potentially carcinogenic effects of some of its ingredients, creosote has meanwhile been banned from cosmetics completely, and medications containing creosote are now prescription-only.

What the pharmacologists detected in Hatshepsut's little bottle was in particular benzo(a)pyrene, a hazardous aromatic hydrocarbon consisting of several carbon rings. "Benzo(a)pyrene is one of the most dangerous carcinogenic substances we know," explained Dr. Wiedenfeld. For example, the risk of contracting lung cancer from cigarette smoke results essentially from this substance.

Did the lotion cause the Pharaoh's death from cancer?

Did Hatshepsut maybe poison herself without knowing it? "There is a lot that speaks for this hypothesis," Dr. Wiedenfeld said. "If you imagine that the Queen had a chronic skin disease and that she found short-term improvement from the salve, she may have exposed herself to a great risk over the years." The Egyptologist also thinks that this is very likely. "We have known for a long time that Hatshepsut had cancer and maybe even died from it," said Michael Höveler-Müller. "We may now know the actual cause."

But at this point, the Bonn scientists can only surmise how Hatshepsut obtained her lotion. "Egyptian physicians were general practitioners and good surgeons, but they were lousy internists," explained Dr. Wiedenfeld. "It is quite possible that they owe their knowledge of certain medications to their contacts with Persia and India where the healing arts were very advanced even in Antiquity."


Story Source:

The above story is based on materials provided by University of Bonn. Note: Materials may be edited for content and length.


Cite This Page:

University of Bonn. "Deadly ancient Egyptian medication? German scientists shed light on dark secret of Queen Hatshepsut's flacon." ScienceDaily. ScienceDaily, 22 August 2011. <www.sciencedaily.com/releases/2011/08/110819131513.htm>.
University of Bonn. (2011, August 22). Deadly ancient Egyptian medication? German scientists shed light on dark secret of Queen Hatshepsut's flacon. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2011/08/110819131513.htm
University of Bonn. "Deadly ancient Egyptian medication? German scientists shed light on dark secret of Queen Hatshepsut's flacon." ScienceDaily. www.sciencedaily.com/releases/2011/08/110819131513.htm (accessed September 2, 2014).

Share This




More Fossils & Ruins News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Did Neanderthals Play Tic-Tac-Toe?

Did Neanderthals Play Tic-Tac-Toe?

Newsy (Sep. 2, 2014) — Artwork found in a Gibraltar cave that was possibly done by Neanderthals suggests they may have been smarter than we all thought. Video provided by Newsy
Powered by NewsLook.com
Millions Of Historical Public Domain Photos Added To Flickr

Millions Of Historical Public Domain Photos Added To Flickr

Newsy (Aug. 30, 2014) — Historian Kalev Leetaru uploaded a large collection of historical photos, images that were previously difficult to collect. Video provided by Newsy
Powered by NewsLook.com
Minds Blown: Scientists Develop Fish That Walk On Land

Minds Blown: Scientists Develop Fish That Walk On Land

Newsy (Aug. 28, 2014) — Canadian scientists looking into the very first land animals took a fish out of water and forced it to walk. Video provided by Newsy
Powered by NewsLook.com
Huge Ancient Wine Cellar Found In Israel

Huge Ancient Wine Cellar Found In Israel

Newsy (Aug. 28, 2014) — An international team uncovered a large ancient wine celler that likely belonged to a Cannonite ruler. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins