Featured Research

from universities, journals, and other organizations

Major brain similarities found in bipolar disorder and schizophrenia

Date:
August 26, 2011
Source:
Royal College of Surgeons in Ireland (RCSI)
Summary:
Researchers have conducted a study which has found striking brain similarities in bipolar disorder and schizophrenia.

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have conducted a study which has found striking brain similarities in bipolar disorder and schizophrenia. The research has also pinpointed for the first time that a process which controls how information is transmitted from neuron to neuron in the brain is altered in both conditions and may potentially contribute to the developments of improved treatments in the future.

The study was the first to look at sub-regions in the part of the brain known as the hippocampus. Abnormalities in the hippocampus are among the most consistent findings in schizophrenia research and are also implicated in bipolar disorder. Certain areas of the hippocampus (cornu ammonis regions 2 and 3) were found to be different, in terms of how their proteins are affected, in people with schizophrenia and bipolar disorder compared to the general population. The differences observed in these regions were found to be almost identical in both conditions. A process which controls how information is transmitted by the shuttling of proteins to and from the synapse (a junction that permits a neuron to pass a signal to another cell) was also found to be is affected in both illnesses.

Professor David Cotter, Department of Psychiatry, RCSI and Beaumont Hospital commented: "Our study is the first to show the depth of protein similarities between schizophrenia and bipolar disorder as they appear in the brain and the processes associated with them. Although, the two conditions present with different symptoms, the research has shown that they are almost identical in terms of how they present in the brain," Professor Cotter concluded.


Story Source:

The above story is based on materials provided by Royal College of Surgeons in Ireland (RCSI). Note: Materials may be edited for content and length.


Journal Reference:

  1. Melanie Fφcking, Patrick Dicker, Jane A. English, K. Oliver Schubert, Michael J. Dunn, David R. Cotter. Common Proteomic Changes in the Hippocampus in Schizophrenia and Bipolar Disorder and Particular Evidence for Involvement of Cornu Ammonis Regions 2 and 3. Archives of General Psychiatry, 68 (5): 477-88

Cite This Page:

Royal College of Surgeons in Ireland (RCSI). "Major brain similarities found in bipolar disorder and schizophrenia." ScienceDaily. ScienceDaily, 26 August 2011. <www.sciencedaily.com/releases/2011/08/110825090236.htm>.
Royal College of Surgeons in Ireland (RCSI). (2011, August 26). Major brain similarities found in bipolar disorder and schizophrenia. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2011/08/110825090236.htm
Royal College of Surgeons in Ireland (RCSI). "Major brain similarities found in bipolar disorder and schizophrenia." ScienceDaily. www.sciencedaily.com/releases/2011/08/110825090236.htm (accessed July 31, 2014).

Share This




More Mind & Brain News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Dieting At A Young Age Might Lead To Harmful Health Habits

Dieting At A Young Age Might Lead To Harmful Health Habits

Newsy (July 30, 2014) — Researchers say women who diet at a young age are at greater risk of developing harmful health habits, including eating disorders and alcohol abuse. Video provided by Newsy
Powered by NewsLook.com
It's Not Just Facebook: OKCupid Experiments With Users Too

It's Not Just Facebook: OKCupid Experiments With Users Too

Newsy (July 29, 2014) — If you've been looking for love online, there's a chance somebody has been looking at how you're looking. Video provided by Newsy
Powered by NewsLook.com
How Your Face Can Leave A Good Or Bad First Impression

How Your Face Can Leave A Good Or Bad First Impression

Newsy (July 29, 2014) — Researchers have found certain facial features can make us seem more attractive or trustworthy. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) — A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins