Featured Research

from universities, journals, and other organizations

Mother's diet influences baby's allergies, research suggests

Date:
September 9, 2011
Source:
Wiley-Blackwell
Summary:
A possible link between what a mother eats during pregnancy and the risk of her child developing allergies has been identified in new research.

A possible link between what a mother eats during pregnancy and the risk of her child developing allergies has been identified in new research published in this month's The Journal of Physiology.

The research found that if a mother's diet contains a certain group of polyunsaturated fatty acids (PUFAs) -- such as those found in fish, walnut oil or flaxseed -- the baby's gut develops differently. The PUFAs are thought to improve how gut immune cells respond to bacteria and foreign substances, making the baby less likely to suffer from allergies.

Until now, several clinical trials have shown that fish and walnut oil supplementation in pregnant women reduces the risk of allergy in their children, but the mechanism was unknown.

"There is intense research interest in maternal diet during pregnancy. In the western diet, the group of polyunsaturated fatty acids that we have shown to help gut function are actually disappearing -- our dietary intake of fish and nut oils is being replaced by corn oils which contain a different kind of fatty acid." Said Dr Gaλlle Boudry, of the INRA research institute in Rennes, France.

"Our study identifies that a certain group of polyunsaturated fatty acids -- known as n-3PUFAs -- causes a change in how a baby's gut develops, which in turn might change how the gut immune system develops. These changes are likely to reduce the risk of developing allergies in later life."

The team found that supplementing a mother's diet with n-3PUFA caused the newborn's gut to become more permeable. A more permeable gut enables bacteria and new substances to pass through the lining of the gut into the bloodstream more easily. These new substances then trigger the baby's immune response and the production of antibodies.

"The end result is that the baby's immune system may develop and mature faster -- leading to better immune function and less likelihood of suffering allergies," added Dr Boudry.

This research adds to previous studies which have shown that an intake of n-3 PUFAs during pregnancy increases gestational length and maturation of the central nervous system of a baby and that their performance on mental tasks also seemed to be improved in childhood.

"Other studies have found that a diet containing fish or walnut oil during pregnancy may make your baby smarter -- our research adds to this, suggesting such supplements also accelerate the development of a healthy immune system to ward off food allergies."

In terms of next steps, the team's findings were based on piglets so research will continue to see if they translate to humans. The porcine intestine is an excellent model of the human gut however, so they are hopeful that the findings can be extrapolated. The team also plans to investigate whether the apparent gut function-boosting effects of n-3PUFA that they have identified in newborns extends into later life.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. F. De Quelen, J. Chevalier, M. Rolli-Derkinderen, J. Mourot, M. Neunlist, G. Boudry. N-3 polyunsaturated fatty acids in the maternal diet modify the post-natal development of nervous regulation of intestinal permeability in piglets. The Journal of Physiology, 2011; DOI: 10.1113/jphysiol.2011.214056

Cite This Page:

Wiley-Blackwell. "Mother's diet influences baby's allergies, research suggests." ScienceDaily. ScienceDaily, 9 September 2011. <www.sciencedaily.com/releases/2011/09/110908161444.htm>.
Wiley-Blackwell. (2011, September 9). Mother's diet influences baby's allergies, research suggests. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2011/09/110908161444.htm
Wiley-Blackwell. "Mother's diet influences baby's allergies, research suggests." ScienceDaily. www.sciencedaily.com/releases/2011/09/110908161444.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Some Positive Ebola News: Outbreak 'Contained' In Nigeria

Newsy (Sep. 30, 2014) — The CDC says a new case of Ebola has not been reported in Nigeria for more than 21 days, leading to hopes the outbreak might be nearing its end. Video provided by Newsy
Powered by NewsLook.com
UN Ebola Mission Head: Immediate Action Is Crucial

UN Ebola Mission Head: Immediate Action Is Crucial

AFP (Sep. 30, 2014) — The newly appointed head of the United Nations Mission for Ebola Emergency Response (UNMEER), Anthony Banbury, outlines operations to tackle the virus. Duration: 00:39 Video provided by AFP
Powered by NewsLook.com
CDC Confirms First Case of Ebola in US

CDC Confirms First Case of Ebola in US

AP (Sep. 30, 2014) — The CDC has confirmed the first diagnosed case of Ebola in the United States. The patient is being treated at a Dallas hospital after traveling earlier this month from Liberia. (Sept. 30) Video provided by AP
Powered by NewsLook.com
New Breast Cancer Drug Extends Lives In Clinical Trial

New Breast Cancer Drug Extends Lives In Clinical Trial

Newsy (Sep. 30, 2014) — In a clinical trial, breast cancer patients lived an average of 15 months longer when they received new drug Perjeta along with Herceptin. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins