Featured Research

from universities, journals, and other organizations

Mother's diet influences baby's allergies, research suggests

Date:
September 9, 2011
Source:
Wiley-Blackwell
Summary:
A possible link between what a mother eats during pregnancy and the risk of her child developing allergies has been identified in new research.

A possible link between what a mother eats during pregnancy and the risk of her child developing allergies has been identified in new research published in this month's The Journal of Physiology.

The research found that if a mother's diet contains a certain group of polyunsaturated fatty acids (PUFAs) -- such as those found in fish, walnut oil or flaxseed -- the baby's gut develops differently. The PUFAs are thought to improve how gut immune cells respond to bacteria and foreign substances, making the baby less likely to suffer from allergies.

Until now, several clinical trials have shown that fish and walnut oil supplementation in pregnant women reduces the risk of allergy in their children, but the mechanism was unknown.

"There is intense research interest in maternal diet during pregnancy. In the western diet, the group of polyunsaturated fatty acids that we have shown to help gut function are actually disappearing -- our dietary intake of fish and nut oils is being replaced by corn oils which contain a different kind of fatty acid." Said Dr Gaλlle Boudry, of the INRA research institute in Rennes, France.

"Our study identifies that a certain group of polyunsaturated fatty acids -- known as n-3PUFAs -- causes a change in how a baby's gut develops, which in turn might change how the gut immune system develops. These changes are likely to reduce the risk of developing allergies in later life."

The team found that supplementing a mother's diet with n-3PUFA caused the newborn's gut to become more permeable. A more permeable gut enables bacteria and new substances to pass through the lining of the gut into the bloodstream more easily. These new substances then trigger the baby's immune response and the production of antibodies.

"The end result is that the baby's immune system may develop and mature faster -- leading to better immune function and less likelihood of suffering allergies," added Dr Boudry.

This research adds to previous studies which have shown that an intake of n-3 PUFAs during pregnancy increases gestational length and maturation of the central nervous system of a baby and that their performance on mental tasks also seemed to be improved in childhood.

"Other studies have found that a diet containing fish or walnut oil during pregnancy may make your baby smarter -- our research adds to this, suggesting such supplements also accelerate the development of a healthy immune system to ward off food allergies."

In terms of next steps, the team's findings were based on piglets so research will continue to see if they translate to humans. The porcine intestine is an excellent model of the human gut however, so they are hopeful that the findings can be extrapolated. The team also plans to investigate whether the apparent gut function-boosting effects of n-3PUFA that they have identified in newborns extends into later life.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. F. De Quelen, J. Chevalier, M. Rolli-Derkinderen, J. Mourot, M. Neunlist, G. Boudry. N-3 polyunsaturated fatty acids in the maternal diet modify the post-natal development of nervous regulation of intestinal permeability in piglets. The Journal of Physiology, 2011; DOI: 10.1113/jphysiol.2011.214056

Cite This Page:

Wiley-Blackwell. "Mother's diet influences baby's allergies, research suggests." ScienceDaily. ScienceDaily, 9 September 2011. <www.sciencedaily.com/releases/2011/09/110908161444.htm>.
Wiley-Blackwell. (2011, September 9). Mother's diet influences baby's allergies, research suggests. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2011/09/110908161444.htm
Wiley-Blackwell. "Mother's diet influences baby's allergies, research suggests." ScienceDaily. www.sciencedaily.com/releases/2011/09/110908161444.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) — Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) — The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) — Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) — New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins