Featured Research

from universities, journals, and other organizations

Terahertz radiation's impact on cellular function and gene expression

Date:
September 13, 2011
Source:
Optical Society of America
Summary:
Relatively little is known about the effect of terahertz radiation on biological systems. A team of researchers have now evaluated the cellular response of mouse stem cells exposed to THz radiation. They reported that temperature increases were minimal, and that heat shock protein expression was unaffected, while the expression of certain other genes showed clear effects of the THz irradiation.

Terahertz (THz) technologies show promise for myriad medical, military, security, and research applications ranging from the detection of cancer to airport security systems to shipment inspection to spectroscopy. Relatively little is known, however, about the effect of THz radiation on biological systems. So a team of researchers, led by Los Alamos National Laboratory, evaluated the cellular response of mouse stem cells exposed to THz radiation.

They applied low-power radiation both from a pulsed broadband (centered at 10 THz) source and from a continuous wave (CW) laser (2.52 THz) source, and applied both modeling and empirical characterization and monitoring techniques to minimize the impact of radiation-induced increases in temperature.

The researchers determined that temperature increases were minimal, and that heat shock protein expression was unaffected, while the expression of certain other genes showed clear effects of the THz irradiation. As the researchers describe in the September issue of the Optical Society's (OSA) open-access journal Biomedical Optics Express, mouse mesenchymal stem cells exposed to THz radiation exhibit specific changes in cellular function closely related to the gene expression. They believe further investigations involving a large number of genes and variation in THz radiation characteristics and exposure duration are needed to generalize their findings. They also say that more direct experimental investigations of THz radiation's ability to induce specific openings of the DNA double strand are needed to fully determine how THz radiation may work through DNA dynamics to influence cellular function.

The team, led by Los Alamos National Lab, worked in collaboration with the Center for Integrated Nanotechnologies, a U.S. Department of Energy, Office of Basic Energy Sciences user facility at Los Alamos and Sandia National Laboratories, and with Harvard Medical School, and Beth Israel Deaconess Medical Center.


Story Source:

The above story is based on materials provided by Optical Society of America. Note: Materials may be edited for content and length.


Journal Reference:

  1. Boian S. Alexandrov, Kim . Rasmussen, Alan R. Bishop, Anny Usheva, Ludmil B. Alexandrov, Shou Chong, Yossi Dagon, Layla G. Booshehri, Charles H. Mielke, M. Lisa Phipps, Jennifer S. Martinez, Hou-Tong Chen, George Rodriguez. Non-thermal effects of terahertz radiation on gene expression in mouse stem cells. Biomedical Optics Express, 2011; 2 (9): 2679 DOI: 10.1364/BOE.2.002679

Cite This Page:

Optical Society of America. "Terahertz radiation's impact on cellular function and gene expression." ScienceDaily. ScienceDaily, 13 September 2011. <www.sciencedaily.com/releases/2011/09/110913103217.htm>.
Optical Society of America. (2011, September 13). Terahertz radiation's impact on cellular function and gene expression. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2011/09/110913103217.htm
Optical Society of America. "Terahertz radiation's impact on cellular function and gene expression." ScienceDaily. www.sciencedaily.com/releases/2011/09/110913103217.htm (accessed September 2, 2014).

Share This




More Matter & Energy News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Australian Airlines Relax Phone Ban Too

Australian Airlines Relax Phone Ban Too

Reuters - Business Video Online (Aug. 26, 2014) Qantas and Virgin say passengers can use their smartphones and tablets throughout flights after a regulator relaxed a ban on electronic devices during take-off and landing. As Hayley Platt reports the move comes as the two domestic rivals are expected to post annual net losses later this week. Video provided by Reuters
Powered by NewsLook.com
Hurricane Marie Brings Big Waves to California Coast

Hurricane Marie Brings Big Waves to California Coast

Reuters - US Online Video (Aug. 26, 2014) Huge waves generated by Hurricane Marie hit the Southern California coast. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Chinese Researchers Might Be Creating Supersonic Submarine

Chinese Researchers Might Be Creating Supersonic Submarine

Newsy (Aug. 26, 2014) Chinese researchers have expanded on Cold War-era tech and are closer to building a submarine that could reach the speed of sound. Video provided by Newsy
Powered by NewsLook.com
Breakingviews: India Coal Strained by Supreme Court Ruling

Breakingviews: India Coal Strained by Supreme Court Ruling

Reuters - Business Video Online (Aug. 26, 2014) An acute coal shortage is likely to be aggravated as India's supreme court declared government coal allocations illegal, says Breakingviews' Peter Thal Larsen. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins