Featured Research

from universities, journals, and other organizations

Earlier male circumcision may help to slow rates of HIV, HPV transmission in South Africa

Date:
October 6, 2011
Source:
H. Lee Moffitt Cancer Center & Research Institute
Summary:
Earlier circumcision of males in South Africa may be a positive step in slowing the spread of both HIV and the human papillomavirus.

According to Anna R. Giuliano, Ph.D., program leader in cancer epidemiology at Moffitt Cancer Center in Tampa, Fla., and colleagues in the Netherlands, earlier circumcision of males in South Africa may be a positive step in slowing the spread of both HIV and the human papillomavirus (HPV). Their commentary and data were published in a recent issue of the British medical journal The Lancet Infectious Diseases (Vol. 11) 581-582.

"Countries with high incidences of HIV also have high incidences of cancer-related HPV," said Giuliano. "This is especially true in South Africa."

Commenting on a study related to circumcision and HIV and HPV transmission, Giuliano and her colleagues note that studies have shown that circumcision of HIV-infected men does not reduce HPV transmission to their female partners. Many factors may account for this lack of efficacy. However, Giuliano and colleagues suggest that the high prevalence of HPV among the HIV-infected men (73 percent in the intervention group and 69 percent in the control group) and the high prevalence of HIV among the female partners of greater than 60 percent, relates to the lack of efficacy of male circumcision. In that study, it was pointed out that the high and sustained prevalence of HPV among the HIV-infected individuals is "likely to overwhelm any preventative effect of circumcision."

"Male circumcision is important for reduction of not only HIV infection but also HPV infection in HIV-negative men and their female partners," said Giuliano. "However, its efficacy seems limited to HIV-negative men. These results suggest the need for early circumcision to achieve maximum effectiveness in populations with a high incidence of HIV and cervical cancer."

For maximum reductions in HIV and HPV infections and related diseases in women, such as cervical cancer, the researchers recommend that both circumcision and HPV vaccination of the male population should be delivered prior to sexual debut.


Story Source:

The above story is based on materials provided by H. Lee Moffitt Cancer Center & Research Institute. Note: Materials may be edited for content and length.


Journal Reference:

  1. AR Giuliano, MF Schim van der Loeff, AG Nyitray. Circumcised HIV-infected men and HPV transmission. The Lancet Infectious Diseases, 2011; 11 (8): 581 DOI: 10.1016/S1473-3099(11)70073-1

Cite This Page:

H. Lee Moffitt Cancer Center & Research Institute. "Earlier male circumcision may help to slow rates of HIV, HPV transmission in South Africa." ScienceDaily. ScienceDaily, 6 October 2011. <www.sciencedaily.com/releases/2011/10/111006133022.htm>.
H. Lee Moffitt Cancer Center & Research Institute. (2011, October 6). Earlier male circumcision may help to slow rates of HIV, HPV transmission in South Africa. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2011/10/111006133022.htm
H. Lee Moffitt Cancer Center & Research Institute. "Earlier male circumcision may help to slow rates of HIV, HPV transmission in South Africa." ScienceDaily. www.sciencedaily.com/releases/2011/10/111006133022.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins