Featured Research

from universities, journals, and other organizations

Vitamin E supplement may increase prostate cancer risk, national U.S. study finds

Date:
October 11, 2011
Source:
Cleveland Clinic
Summary:
Men who take a daily vitamin E supplement -- a regimen once thought to reduce cancer risk -- face an increased risk of prostate cancer, according to results of a large national study. The finding comes from a report summarizing the latest results of the Selenium and Vitamin E Cancer Prevention Trial (SELECT).

Cleveland: Men who take a daily vitamin E supplement -- a regimen once thought to reduce cancer risk -- face an increased risk of prostate cancer, according to results of a large national study.

The finding comes from a report summarizing the latest results of the Selenium and Vitamin E Cancer Prevention Trial (SELECT). Eric Klein, M.D., chair of the Glickman Urological and Kidney Institute at Cleveland Clinic, is the lead author.

SELECT began in 2001 to test earlier research suggesting selenium and vitamin E supplements may reduce the risk of developing certain cancers. Some vitamin supplements containing enhanced levels of selenium and vitamin E were marketed to consumers during this time period with claims of reducing cancer risk.

The paper, which will appear in the October 12 edition of the Journal of the American Medical Association, found that a group of men taking a daily dose of 400 IU of vitamin E from 2001 to 2008 had 17 percent more cases of prostate cancer than men who took a placebo.

"For the typical man, there appears to be no benefit in taking vitamin E, and in fact, there may be some harm," said Dr. Klein, an internationally renowned prostate cancer expert who served as the national study coordinator.

SELECT tracked more than 35,000 men at locations across the United States, Canada, and Puerto Rico who took daily doses through the Fall of 2008. The trial was funded by the National Cancer Institute and administered by the Southwest Oncology Group (SWOG), an international network of research institutions with study sites in 400 locations across the U.S., Puerto Rico and Canada.

The men were divided into four groups: vitamin E and Selenium; vitamin E alone; selenium alone; and placebo. The group taking vitamin E was the only group shown to have a statistically significant increased risk of prostate cancer.

Prostate cancer is the most common non-skin cancer in American men with a current lifetime risk of 16 percent. For 2011 it is estimated 240,000 new cases and 33,000 deaths will result in the U.S.

Men who participated in the SELECT trail can find more information at www.SWOG.org.


Story Source:

The above story is based on materials provided by Cleveland Clinic. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. A. Klein, I. M. Thompson, C. M. Tangen, J. J. Crowley, M. S. Lucia, P. J. Goodman, L. Minasian, L. G. Ford, H. L. Parnes, J. M. Gaziano, D. D. Karp, M. M. Lieber, P. J. Walther, L. Klotz, J. K. Parsons, J. L. Chin, A. Darke, S. M. Lippman, G. E. Goodman, F. L. Meyskens, L. H. Baker. Vitamin E and the Risk of Prostate Cancer: Results of The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA, 2011; 306 (14): 1549-1556 DOI: 10.1001/jama.2011.1437

Cite This Page:

Cleveland Clinic. "Vitamin E supplement may increase prostate cancer risk, national U.S. study finds." ScienceDaily. ScienceDaily, 11 October 2011. <www.sciencedaily.com/releases/2011/10/111011163055.htm>.
Cleveland Clinic. (2011, October 11). Vitamin E supplement may increase prostate cancer risk, national U.S. study finds. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2011/10/111011163055.htm
Cleveland Clinic. "Vitamin E supplement may increase prostate cancer risk, national U.S. study finds." ScienceDaily. www.sciencedaily.com/releases/2011/10/111011163055.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

More Coverage


Study Shows Increased Prostate Cancer Risk from Vitamin E Supplements

Oct. 11, 2011 Men who took 400 international units of vitamin E daily had more prostate cancers compared to men who took a placebo. The findings showed that, per 1,000 men, there were 76 prostate cancers in men ... read more
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins