Featured Research

from universities, journals, and other organizations

First Ebola-like virus native to Europe discovered

Date:
October 22, 2011
Source:
Columbia University's Mailman School of Public Health
Summary:
Researchers have discovered a new Ebola-like virus -- Lloviu virus -- in bats from northern Spain. Lloviu virus is the first known filovirus native to Europe. Filoviruses, which include well-known viruses like Ebola and Marburg, are among the deadliest pathogens in humans and non-human primates, and are generally found in East Africa and the Philippines. The findings thus expand the natural geographical distribution of filoviruses.

A team of international researchers has discovered a new Ebola-like virus -- Lloviu virus -- in bats from northern Spain. Lloviu virus is the first known filovirus native to Europe, they report in a study published in the journal PLOS Pathogens.

Related Articles


The study was a collaboration among scientists at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health, the Instituto de Salud Carlos III (ISCIII) in Spain, Roche Life Sciences, Centro de Investigación Príncipe Felipe, Grupo Asturiano para el Estudio y Conservación de los Murciélagos, Consejo Suerior de Investigaciones Científicas and the Complutense University in Spain.

Filoviruses, which include well-known viruses like Ebola and Marburg, are among the deadliest pathogens in humans and non-human primates, and are generally found in East Africa and the Philippines. The findings thus expand the natural geographical distribution of filoviruses.

"The study is an opportunity to advance the knowledge of filoviruses' natural cycle," said Ana Negredo, one of the first authors of the study.

Scientists at ISCIII analyzed lung, liver, spleen, throat, brain and rectal samples from 34 bats found in caves in Asturias and Cantabria, Spain, following bat die-offs in France, Spain and Portugal in 2002 affecting mainly one bat species.

They screened these samples for a wide range of viruses using the polymerase chain reaction, a molecular technique that allows scientists to amplify genetic material, and. detected a filovirus. Filoviruses include ebolaviruses and marburgviruses, two viruses associated with severe disease in humans and other primates..

CII scientists used high-throughput sequencing to characterize the virus' genome. When they compared it to other well-known filovirus genomes, they found that Lloviu virus represents a class of viruses distantly related to all ebolaviruses and that it may have diverged from ebolaviruses about 68,000 years ago.

"The detection of this novel filovirus in Spain is intriguing because it is completely outside of its previously described range. We need to ascertain whether other filoviruses native to Europe exist, and more importantly, if and how it causes disease," said Gustavo Palacios, the other first author of the study.

Filoviruses typically do not make bats sick, but because the team of researchers only detected Lloviu virus in bats that had died and whose tissues showed signs of an immune response, they think Lloviu may be a cause for concern. They also did not detect Lloviu virus in samples of almost 1,300 healthy bats.

Bats have important roles in plant pollination, spreading plant seeds and controlling insect populations, and pathogens that attack bat populations could have dramatic ecological and health-related consequences.

"The Lloviu virus discovery highlights how much we still need to learn about the world of emerging infectious diseases and the importance of global collaboration and the One Health initiative in addressing the challenge," said CII Director Dr. Ian Lipkin.

This research was funded by the Defense Threat Reduction Agency, USAID PREDICT, the RICET Network on Tropical Diseases and the Ministerio de Educación y Ciencia in Spain.


Story Source:

The above story is based on materials provided by Columbia University's Mailman School of Public Health. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ana Negredo, Gustavo Palacios, Sonia Vázquez-Morón, Félix González, Hernán Dopazo, Francisca Molero, Javier Juste, Juan Quetglas, Nazir Savji, Maria de la Cruz Martínez, Jesus Enrique Herrera, Manuel Pizarro, Stephen K. Hutchison, Juan E. Echevarría, W. Ian Lipkin, Antonio Tenorio. Discovery of an Ebolavirus-Like Filovirus in Europe. PLoS Pathogens, 2011; 7 (10): e1002304 DOI: 10.1371/journal.ppat.1002304

Cite This Page:

Columbia University's Mailman School of Public Health. "First Ebola-like virus native to Europe discovered." ScienceDaily. ScienceDaily, 22 October 2011. <www.sciencedaily.com/releases/2011/10/111020191850.htm>.
Columbia University's Mailman School of Public Health. (2011, October 22). First Ebola-like virus native to Europe discovered. ScienceDaily. Retrieved April 19, 2015 from www.sciencedaily.com/releases/2011/10/111020191850.htm
Columbia University's Mailman School of Public Health. "First Ebola-like virus native to Europe discovered." ScienceDaily. www.sciencedaily.com/releases/2011/10/111020191850.htm (accessed April 19, 2015).

Share This


More From ScienceDaily



More Plants & Animals News

Sunday, April 19, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Un-Bee-Lievable: Bees on the Loose After Washington Truck Crash

Un-Bee-Lievable: Bees on the Loose After Washington Truck Crash

Reuters - US Online Video (Apr. 17, 2015) — A truck carrying honey bees overturns near Lynnwood, Washington, spreading boxes of live bees across the highway. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) — Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Dog Flu Spreading in Midwestern States

Dog Flu Spreading in Midwestern States

AP (Apr. 17, 2015) — Dog flu is spreading in several Midwestern states. Dog daycare centers and veterinary offices are taking precautions. (April 17) Video provided by AP
Powered by NewsLook.com
Raw: Rare Whale Spotted in Gulf of Mexico

Raw: Rare Whale Spotted in Gulf of Mexico

AP (Apr. 17, 2015) — Researchers from the E/V Nautilus had quite a surprise Tuesday, when a curious sperm whale swam around their remotely operated vehicle in the Gulf of Mexico. Cameras captured the encounter. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins