Featured Research

from universities, journals, and other organizations

Saliva HIV test passes the grade

Date:
January 24, 2012
Source:
McGill University Health Centre
Summary:
A saliva test used to diagnose the human immunodeficiency virus (HIV), is comparable in accuracy to the traditional blood test, according to a new study. The meta-analysis, which compared studies worldwide, showed that the saliva HIV test had the same accuracy as the blood test for high-risk populations. The study has major implications for countries that wish to adopt self-testing strategies for HIV.

A saliva test used to diagnose the human immunodeficiency virus (HIV), is comparable in accuracy to the traditional blood test, according to a new study led by the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University. The meta-analysis, which compared studies worldwide, showed that the saliva HIV test, OraQuick HIV1/2, had the same accuracy as the blood test for high-risk populations. The test sensitivity was slightly reduced for low risk populations.

The study, published in this week's issue of The Lancet Infectious Diseases, has major implications for countries that wish to adopt self-testing strategies for HIV.

"Testing is the cornerstone of prevention, treatment and care strategies," says the study's lead author, Dr. Nitika Pant Pai, a medical scientist at the RI-MUHC and assistant professor of Medicine at McGill University. "Although previous studies have shown that the oral fluid-based OraQuick HIV1/2 test has great promise, ours is the first to evaluate its potential at a global level."

Dr. Pant Pai and her colleagues analyzed and synthesized real-life field research data from five worldwide databases. Their findings showed that the saliva test is 99 percent accurate for HIV in high risk populations, and about 97 percent in low risk populations.

The oral HIV test has become one of the most popular tests because of its acceptability and ease of use. It is non-invasive, pain-free, and convenient and produces results in 20 minutes. "Getting people to show up for HIV testing at public clinics has been difficult because of visibility, stigma, lack of privacy and discrimination. A confidential testing option such as self-testing could bring an end to the stigmatization associated with HIV testing," says Dr. Pant Pai, whose work is supported by a Grand Challenges Canada's Rising Star in Global Health Award. "There is a huge global momentum for alternate HIV self-testing strategies that can inform people of their status."

High risk populations fuel the expansion of HIV epidemics but they face widespread discrimination, violence and social marginalization from healthcare services. UNAIDS estimates that globally, 90% of men who have sex with men lack access to the most basic sexual health services. "Oral HIV tests can be a powerful tool for high risk populations, but self-testing must be accompanied by linkage to care to achieve good health outcomes," says the study's co-author Dr. Rosanna Peeling, Professor and Chair of Diagnostics Research at the London School of Hygiene & Tropical Medicine.


Story Source:

The above story is based on materials provided by McGill University Health Centre. Note: Materials may be edited for content and length.


Journal Reference:

  1. Dr Nitika Pant Pai, Bhairavi Balram, Sushmita Shivkumar, Jorge Luis Martinez-Cajas, Christiane Claessens, Gilles Lambert et al. Head-to-head comparison of accuracy of a rapid point-of-care HIV test with oral versus whole-blood specimens: a systematic review and meta-analysis. The Lancet Infectious Diseases, Jan 24, 2012 DOI: 10.1016/S1473-3099(11)70368-1

Cite This Page:

McGill University Health Centre. "Saliva HIV test passes the grade." ScienceDaily. ScienceDaily, 24 January 2012. <www.sciencedaily.com/releases/2012/01/120124113220.htm>.
McGill University Health Centre. (2012, January 24). Saliva HIV test passes the grade. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2012/01/120124113220.htm
McGill University Health Centre. "Saliva HIV test passes the grade." ScienceDaily. www.sciencedaily.com/releases/2012/01/120124113220.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins