Featured Research

from universities, journals, and other organizations

Who will benefit from stroke drug? New score can help decide

Date:
February 6, 2012
Source:
American Academy of Neurology (AAN)
Summary:
A new scoring method can help doctors quickly decide which stroke patients will respond well to the clot-busting drug alteplase, according to a new study.

A new scoring method can help doctors quickly decide which stroke patients will respond well to the clot-busting drug alteplase, according to a study published in the February 7, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Related Articles


The DRAGON score was 86 percent accurate in predicting the outcome three months after people had the stroke and received the drug within four-and-a-half hours after their first stroke symptoms.

"The DRAGON score is simple and fast to perform, it has no cost, and it consists solely of factors that are known when the patient is admitted to the hospital or soon after," said study author Daniel Strbian, MD, PhD, of Helsinki University Central Hospital in Finland. "We found that we could determine the score in less than a minute. This can help the doctor, the patient, and the family to evaluate the situation, make choices and give the most relevant treatment with the greatest speed."

Strbian said the score can help with the decision to try additional therapies when the likelihood is high that alteplase alone will not provide a good outcome.

The study involved 1,319 people with ischemic stroke with an average age of 69 who were treated with alteplase. Participants were given a score of zero to 10 based on their age, glucose level, time since stroke symptoms started, the severity of the stroke and other factors. The higher the score was, the more likely the person was to have a bad outcome three months later. A bad outcome was defined as being dead or being bedridden, incontinent and requiring constant nursing care and attention.

A total of 96 percent of those with scores of zero to two had a good outcome three months later. A good outcome was defined as being independent in daily activities. None of the people with DRAGON scores of eight to 10 had good outcomes three months later.

The score was also tested on a second group of 333 people at a hospital in Switzerland, with similar results.

The study was supported by Helsinki University Central Hospital, the Sigrid Juselius Foundation, the Finnish Medical Foundation and the Yrjö Jahnsson Foundation.


Story Source:

The above story is based on materials provided by American Academy of Neurology (AAN). Note: Materials may be edited for content and length.


Journal Reference:

  1. D. Strbian, A. Meretoja, F. J. Ahlhelm, J. Pitkaniemi, P. Lyrer, M. Kaste, S. Engelter, T. Tatlisumak. Predicting outcome of IV thrombolysis-treated ischemic stroke patients: The DRAGON score. Neurology, 2012; 78 (6): 427 DOI: 10.1212/WNL.0b013e318245d2a9

Cite This Page:

American Academy of Neurology (AAN). "Who will benefit from stroke drug? New score can help decide." ScienceDaily. ScienceDaily, 6 February 2012. <www.sciencedaily.com/releases/2012/02/120206174207.htm>.
American Academy of Neurology (AAN). (2012, February 6). Who will benefit from stroke drug? New score can help decide. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2012/02/120206174207.htm
American Academy of Neurology (AAN). "Who will benefit from stroke drug? New score can help decide." ScienceDaily. www.sciencedaily.com/releases/2012/02/120206174207.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) — A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins