Featured Research

from universities, journals, and other organizations

Graphene: Potential for modelling cell membrane systems

Date:
March 21, 2012
Source:
Toyohashi University of Technology
Summary:
Intriguing properties of graphene -— a single atomic-layer of carbon -— such as high electron mobility and fluorescence quenching are being exploited for biosensing and analysis of nucleotides, peptides, and proteins.

Fig.1. (A) Scanning electron microscope image of GO flakes dropped onto a SiO2/Si substrate. (B) Atomic force microscope topography and (C) structural model of DOPC bilayer membranes on GO/SiO2/Si.
Credit: Copyright : Toyohashi University of Technology

At Toyohashi University of Technology the intriguing properties of graphene -- a single atomic-layer of carbon -- such as high electron mobility and fluorescence quenching are being exploited for biosensing and analysis of nucleotides, peptides, and proteins.

Related Articles


Graphene could also play an important role in the modelling of cell membranes. For example, the lipid bilayer is the fundamental structure of cell membranes, and the structure and dynamic of bilayer membranes govern the transport of materials and information in and out of cells.

Ryugo Tero and his colleagues in the Graphene Research Group at Toyohashi University of Technology have established a new procedure to fabricate artificial planar lipid membranes on graphene oxide (GO) and reduced graphene oxide (r-GO) as a means of detecting biomolecules such as lipids and proteins on and inside lipid bilayers.

An aqueous solution of GO was prepared by chemical exfoliation and dropped onto a thermally oxidized and cleaned SiO2/Si substrate (Fig.1A). The resulting GO/SiO2/Si was incubated in a vesicle suspension of phospholipid (dioleoylphosphatidylcholine: DOPC). Subsequent observation with an atomic force fluorescence microscopy (Fig.1B) and revealed the presence of two planar DOPC bilayer membranes stacked on GO with the assistance of calcium ion (5 mM), and that the DOPC bilayers on GO were fluid and continuous with the surrounding DOPC bilayers on the bare SiO2 surfaces (Fig. 1C).

Lipid bilayer/monolayer stacking structures were obtained on hydrophobic r-GO, which was produced by reducing GO with hydrazine vapour. Artificial lipid bilayers on graphene and its derivatives could be a new cell membrane model system for the researche on fundamental processes in cell membrane reactions.

Further information

These results will be a part of the presentation in MRS (Material Research Society) Spring Meeting 2012 at San Francisco on April 12 (Symposium EE: New Functional Nanocarbon Devices).

・ Y. Okamoto, K. Tsuzuki, S. Iwasa, R. Ishikawa, A. Sandhu and R. Tero.

・ IOP Journal of Physics: Conference Series (in press).

・ K. Tsuzuki, Y. Okamoto, S. Iwasa, R. Ishikawa, A. Sandhu and R. Tero.

・ IOP Journal of Physics: Conference Series (in press).

・ Electronics-Inspired Interdisciplinary Research Institute (EIIRIS), Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku-cho, Toyohashi, Aichi 441-8580, Japan


Story Source:

The above story is based on materials provided by Toyohashi University of Technology. Note: Materials may be edited for content and length.


Cite This Page:

Toyohashi University of Technology. "Graphene: Potential for modelling cell membrane systems." ScienceDaily. ScienceDaily, 21 March 2012. <www.sciencedaily.com/releases/2012/03/120321152558.htm>.
Toyohashi University of Technology. (2012, March 21). Graphene: Potential for modelling cell membrane systems. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2012/03/120321152558.htm
Toyohashi University of Technology. "Graphene: Potential for modelling cell membrane systems." ScienceDaily. www.sciencedaily.com/releases/2012/03/120321152558.htm (accessed October 24, 2014).

Share This



More Matter & Energy News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3D Printed Instruments Make Sweet Music in Sweden

3D Printed Instruments Make Sweet Music in Sweden

Reuters - Innovations Video Online (Oct. 23, 2014) Students from Lund University's Malmo Academy of Music are believed to be the world's first band to all use 3D printed instruments. The guitar, bass guitar, keyboard and drums were built by Olaf Diegel, professor of product development, who says 3D printing allows musicians to design an instrument to their exact specifications. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Chameleon Camouflage to Give Tanks Cloaking Capabilities

Chameleon Camouflage to Give Tanks Cloaking Capabilities

Reuters - Innovations Video Online (Oct. 22, 2014) Inspired by the way a chameleon changes its colour to disguise itself; scientists in Poland want to replace traditional camouflage paint with thousands of electrochromic plates that will continuously change colour to blend with its surroundings. The first PL-01 concept tank prototype will be tested within a few years, with scientists predicting that a similar technology could even be woven into the fabric of a soldiers' clothing making them virtually invisible to the naked eye. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Jet Sales Lift Boeing Profit 18 Pct.

Jet Sales Lift Boeing Profit 18 Pct.

Reuters - Business Video Online (Oct. 22, 2014) Strong jet demand has pushed Boeing to raise its profit forecast for the third time, but analysts were disappointed by its small cash flow. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Internet of Things Aims to Smarten Your Life

Internet of Things Aims to Smarten Your Life

AP (Oct. 22, 2014) As more and more Bluetooth-enabled devices are reaching consumers, developers are busy connecting them together as part of the Internet of Things. (Oct. 22) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins