Featured Research

from universities, journals, and other organizations

Writing a landmark sequel to 'The Book of Life'

Date:
May 2, 2012
Source:
American Chemical Society
Summary:
Scientists are announcing the roadmap, policies and procedures for an ambitious international project aiming to compile a landmark sequel to "The Book of Life." The follow-up to the Human Genome Project, which decoded all human genes, involves identifying and profiling all of the proteins produced by the thousands of genes in the human chromosomes. It is called the Chromosome-Centric Human Proteome Project.

Scientists are announcing the roadmap, policies and procedures for an ambitious international project that aims to compile a landmark sequel to "The Book of Life." The follow-up to the Human Genome Project, which decoded all of the genes that make up humans, involves identifying and profiling all of the proteins produced by the thousands of genes bundled together in all of the human chromosomes. Called the Chromosome-Centric Human Proteome Project (C-HPP), it is the topic of an article in ACS' Journal of Proteome Research.

William Hancock, Young-Ki Paik and colleagues explain that C-HPP's goal is the next logical step after the 2001 deciphering of the human genome -- a step critical for applying that genetic knowledge in medicine. Genes contain instructions for making proteins, the biological workhorses that influence every aspect of health and disease. Hancock, Paik and colleagues formed C-HPP, an international group of 20 scientific teams, to coordinate efforts to decode this full complement of human, chromosome-encoded proteins, termed the "proteome."

C-HPP's first target will be thousands of "missing" proteins -- proteins that should exist, based on the instructions in genes and other genetic evidence, but remain undiscovered. C-HPP will also help determine what these proteins do in health and disease. The article notes that the Journal of Proteome Research and its publisher, the American Chemical Society, will support C-HPP by publishing results of this work and stimulating recruitment of additional research teams.

The researchers acknowledge funding from Korea's Ministry of Education, Science and Technology and Ministry of Health and Welfare.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Young-Ki Paik, Gilbert S. Omenn, Mathias Uhlen, Samir Hanash, György Marko-Varga, Ruedi Aebersold, Amos Bairoch, Tadashi Yamamoto, Pierre Legrain, Hyoung-Joo Lee, Keun Na, Seul-Ki Jeong, Fuchu He, Pierre-Alain Binz, Toshihide Nishimura, Paul Keown, Mark S. Baker, Jong Shin Yoo, Jerome Garin, Alexander Archakov, John Bergeron, Ghasem Hosseini Salekdeh, William S. Hancock. Standard Guidelines for the Chromosome-Centric Human Proteome Project. Journal of Proteome Research, 2012; 11 (4): 2005 DOI: 10.1021/pr200824a

Cite This Page:

American Chemical Society. "Writing a landmark sequel to 'The Book of Life'." ScienceDaily. ScienceDaily, 2 May 2012. <www.sciencedaily.com/releases/2012/05/120502123516.htm>.
American Chemical Society. (2012, May 2). Writing a landmark sequel to 'The Book of Life'. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2012/05/120502123516.htm
American Chemical Society. "Writing a landmark sequel to 'The Book of Life'." ScienceDaily. www.sciencedaily.com/releases/2012/05/120502123516.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) — As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) — Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
U.S. Food Makers Surpass Calorie-Cutting Pledge

U.S. Food Makers Surpass Calorie-Cutting Pledge

Newsy (Sep. 18, 2014) — Sixteen large food and beverage companies in the United States that committed to cut calories in their products far surpassed their target. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) — Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins