Featured Research

from universities, journals, and other organizations

Pre-test genetic counseling increases cancer knowledge for BRCA patients

Date:
August 15, 2012
Source:
Moffitt Cancer Center
Summary:
Researchers have found that when breast cancer patients are offered pre-test genetic counseling before definitive breast cancer surgery, patients exhibited decreases in distress. Those offered pre-test genetic counseling after surgery improved their informed decision-making. Patients in both groups showed increases in their cancer knowledge with pre-test genetic counseling.

Researchers at Moffitt Cancer Center have found that when breast cancer patients are offered pre-test genetic counseling before definitive breast cancer surgery, patients exhibited decreases in distress. Those offered pre-test genetic counseling after surgery improved their informed decision-making. Patients in both groups showed increases in their cancer knowledge with pre-test genetic counseling.

Related Articles


The study, funded by the American Cancer Society, appeared in a recent issue of the Annals of Surgical Oncology.

Given the role of breast cancer gene status in treatment and risk management, breast cancer patients with certain risk factors may benefit from pre-test genetic counseling and genetic testing at or near the time of initial diagnosis, suggested the researchers.

"However, health care providers may be concerned that women with cancer may be at increased risk for distress, particularly if genetic counseling and genetic testing occur at a time near cancer diagnosis and treatment," said study lead co-author Susan T. Vadaparampil, Ph.D., an associate member of Health Outcomes & Behavior at Moffitt. "Yet, few studies have examined whether this is the case, and little is known about the specific impact of pre-test genetic counseling on cancer knowledge, psychosocial adjustment and decision-making about genetic testing for breast cancer patients before or during treatment."

To address this question, Vadaparampil and colleagues recently completed a study of 103 patients, 87 who had undergone surgery and 16 who had not. They ranged in age from 24 to 69. Patients enrolled in this study met with a master's degree-level, trained genetic health professional to obtain a risk assessment based on personal and family genetic history. Patients also received education about hereditary breast and ovarian cancer and discussed the limitations of genetic testing.

"Before surgery, patients may feel overwhelmed by additional risk information and surgical treatment implications presented during genetic counseling," explained study lead co-author Juliette Christie, Ph.D., a post-doctoral fellow in Moffitt's Behavioral Oncology Training Program. "After surgery, patients may be concerned about their personal and family member's genetic vulnerability."

"When speaking with a before-surgery patient, genetic counselors may need to focus on addressing perceived risks associated with genetic testing and how those align with patient values," Vadaparampil said. "Protocols may need to be adapted to meet the specific needs and perspectives of before-surgery breast cancer patients to ensure timely and effective decision-making after pre-test genetic counseling."

The researchers reported that "trends suggest pre-test genetic counseling decreases overall decisional conflict for after-surgery patients … and it is possible that (these) patients gain increased understanding of the benefits and risks of previous and potential treatment and surgical options."

In this study, both before- and after-surgery patient groups reported increases in cancer knowledge after pre-test genetic counseling. Before-surgery patients reported decreases in cancer-related distress and intrusive thoughts.

"Our data suggest that in the weeks following pre-test genetic counseling, cancer-related knowledge in both before- and after-surgery groups increased, distress in before-surgery patients decreased, and informed decision-making in after-surgery patients improved," concluded the authors.


Story Source:

The above story is based on materials provided by Moffitt Cancer Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Juliette Christie PhD, Gwendolyn P. Quinn PhD, Teri Malo PhD, Ji-Hyun Lee PhD, Xiuhua Zhao MPH, Jessica McIntyre BA, Jennifer Brzosowicz MS, CGC, Paul B. Jacobsen PhD, Susan T. Vadaparampil PhD. Cognitive and Psychological Impact of BRCA Genetic Counseling in Before and After Definitive Surgery Breast Cancer Patients. Annals of Surgical Oncology, Online First - July , 2012 [link]

Cite This Page:

Moffitt Cancer Center. "Pre-test genetic counseling increases cancer knowledge for BRCA patients." ScienceDaily. ScienceDaily, 15 August 2012. <www.sciencedaily.com/releases/2012/08/120815102844.htm>.
Moffitt Cancer Center. (2012, August 15). Pre-test genetic counseling increases cancer knowledge for BRCA patients. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2012/08/120815102844.htm
Moffitt Cancer Center. "Pre-test genetic counseling increases cancer knowledge for BRCA patients." ScienceDaily. www.sciencedaily.com/releases/2012/08/120815102844.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins