Featured Research

from universities, journals, and other organizations

New antibacterial coating for sutures could reduce infections after surgery

Date:
August 29, 2012
Source:
American Chemical Society
Summary:
Responding to an urgent need for better antibacterial coatings on surgical sutures, scientists are reporting the discovery of a new coating that is almost 1,000 times more effective than the most widely used commercial coating.

Responding to an urgent need for better antibacterial coatings on surgical sutures, scientists are reporting the discovery of a new coating that is almost 1,000 times more effective than the most widely used commercial coating.
Credit: © uwimages / Fotolia

Responding to an urgent need for better antibacterial coatings on surgical sutures, scientists are reporting the discovery of a new coating that is almost 1,000 times more effective than the most widely used commercial coating.

Their report appears in ACS' journal Langmuir.

Professor Gregory Tew, who is from UMass-Amherst, and colleagues explain that infection at the site of surgical incisions is one of the most common post-surgical complications that keep patients hospitalized longer and boost hospital bills. The most common antibiotic coating contains triclosan, but its use in many consumer products over the years has led to the emergence of strains of bacteria that shrug off its effects.

Triclosan also can be absorbed into the body, raising concerns about possible adverse health effects. Another downside to triclosan: It slows the growth of bacteria, but does not actually kill those already present. That's why the scientists turned to PAMBM, a new substance designed from naturally occurring antimicrobial peptides that can kill a wide range of bacteria. And because of the way it works, PAMBM has a very low chance of causing bacterial resistance and the emergence of so-called superbugs.

The report described laboratory tests in which PAMBM greatly reduced the amount of bacteria compared to triclosan. In a head-to-head test with triclosan-coated sutures, those coated with PAMBM were much more effective against bacteria. "As bacterial resistance to current agents continues to increase and with resistance to triclosan now documented, the discovery of new antimicrobial agents that remain active in biomedical device coatings is essential," say the researchers.

The authors acknowledge funding from the National Science Foundation.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Yan Li, Kushi N. Kumar, Jeffrey M. Dabkowski, Meagan Corrigan, Richard W. Scott, Klaus Nόsslein, Gregory N. Tew. New Bactericidal Surgical Suture Coating. Langmuir, 2012; 28 (33): 12134 DOI: 10.1021/la302732w

Cite This Page:

American Chemical Society. "New antibacterial coating for sutures could reduce infections after surgery." ScienceDaily. ScienceDaily, 29 August 2012. <www.sciencedaily.com/releases/2012/08/120829131659.htm>.
American Chemical Society. (2012, August 29). New antibacterial coating for sutures could reduce infections after surgery. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2012/08/120829131659.htm
American Chemical Society. "New antibacterial coating for sutures could reduce infections after surgery." ScienceDaily. www.sciencedaily.com/releases/2012/08/120829131659.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) — Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Nigeria Ups Ebola Stakes on 1st Death

Nigeria Ups Ebola Stakes on 1st Death

Reuters - Business Video Online (July 29, 2014) — Nigerian authorities have shut and quarantined a Lagos hospital where a Liberian man died of the Ebola virus, the first recorded case of the highly-infectious disease in Africa's most populous economy. David Pollard reports Video provided by Reuters
Powered by NewsLook.com
Running 5 Minutes A Day Might Add Years To Your Life

Running 5 Minutes A Day Might Add Years To Your Life

Newsy (July 29, 2014) — According to a new study, just five minutes of running or jogging a day could add years to your life. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Poses Little Threat To U.S.: CDC

Ebola Outbreak Poses Little Threat To U.S.: CDC

Newsy (July 29, 2014) — The Ebola outbreak in West Africa poses little threat to Americans, according to officials with the Centers for Disease Control and Prevention. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins