Featured Research

from universities, journals, and other organizations

Sleep apnea linked with increased risk of cancer death

Date:
September 4, 2012
Source:
European Lung Foundation
Summary:
Sleep apnea severity has been associated with increased cancer mortality in a new study.

Sleep apnea severity has been associated with increased cancer mortality in a new study.

The research, which will be presented today (Tuesday 4 September 2012) at the European Respiratory Society's (ERS) Annual Congress in Vienna, adds to evidence presented earlier this year highlighting a link between severe sleep apnea and cancer.

Two further studies presented at the ERS Congress, also show evidence suggesting an increase in cancer incidence among sleep apnea patients and an association between the spread of cancer and sleep apnea.

In the first study, over 5,600 patients from 7 different sleep clinics in Spain were analysed to investigate the link between sleep apnea and cancer mortality.

The severity of sleep apnea, was then measured, using an hypoxaemia index. This index measures the amount of time during the night that a person suffers from low levels of oxygen in the blood (less than 90% oxygen saturation).

The results showed that people with sleep apnea who spent more than 14% of their sleep with levels of oxygen saturation below 90% (usually severe sleep apnea patients) had approximately double the relative risk of death due to cancer (odds ratio 1.94), than people without sleep apnea. The results showed that this association was even higher in men and younger people.

People with sleep apnea can be treated using continuous positive airway pressure (CPAP) therapy, which generates a stream of air to keep the upper airways open during sleep. In the first study, patients who were not using this device consistently had an increased relative risk (odds ratio 2.56) of death from cancer.

Lead author, Dr Miguel Angel Martinez-Garcia from La Fe University Hospital in Valencia, Spain, said: "We found a significant increase in the relative risk of dying from cancer in people with sleep apnea. This adds to evidence presented earlier this year that found for the first time a link between cancer and sleep apnea mortality. Our research has only found an association between these disorders but this does not mean that sleep apnea causes cancer.

Similar results were also found in the second study which showed an increase in all-type cancer incidence in people with severe sleep apnea. The link was present even when factors such as age, sex, weight and other comorbidities of participants, were controlled for.

Lead author, Dr Francisco Campos-Rodriguez from Valme University Hospital in Seville, Spain, said: "Further studies are necessary to corroborate our results and analyse the role of CPAP treatment on this association. We hope the findings of our studies will encourage people to get their sleep apnea diagnosed and treated early to help maintain a good quality of life."

In a third study, researchers used a mouse model of skin cancer (melanoma) to investigate tumour spread (metastasis) and whether this was associated with sleep apnea.

The results showed that the spread of cancer was more abundant in mice that had been subjected to intermittent hypoxic air, with low levels of oxygen as in sleep apnea, than those who breathed normal air during the experiment.

Lead author, Professor Ramon Farre from University of Barcelona in Spain, said: "The data from this study in animals strongly suggests a link between the spread of cancer and sleep apnea. This provides strong evidence to encourage further study in this area to understand in more detail the links between sleep apneoa and cancer."


Story Source:

The above story is based on materials provided by European Lung Foundation. Note: Materials may be edited for content and length.


Cite This Page:

European Lung Foundation. "Sleep apnea linked with increased risk of cancer death." ScienceDaily. ScienceDaily, 4 September 2012. <www.sciencedaily.com/releases/2012/09/120904100149.htm>.
European Lung Foundation. (2012, September 4). Sleep apnea linked with increased risk of cancer death. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2012/09/120904100149.htm
European Lung Foundation. "Sleep apnea linked with increased risk of cancer death." ScienceDaily. www.sciencedaily.com/releases/2012/09/120904100149.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins