Featured Research

from universities, journals, and other organizations

'Foreign' proteins are also implicated in Alzheimer's disease

Date:
September 21, 2012
Source:
Medical University of Vienna
Summary:
Neurodegenerative diseases such as Alzheimer’s or Parkinson’s are characterised by the loss of nerve cells and the deposition of proteins in the brain tissue. Scientists have now demonstrated that Alzheimer’s disease does not just – as previously believed – involve the proteins that are attributed to Alzheimer’s, but instead the condition can involve a mixture of interacting proteins from different neurodegenerative diseases.

Neurodegenerative diseases such as Alzheimer's or Parkinson's are characterised by the loss of nerve cells and the deposition of proteins in the brain tissue. A group of researchers led by Gabor G. Kovacs from the Clinical Institute of Neurology at the MedUni Vienna has now demonstrated that Alzheimer's disease does not just -- as previously believed -- involve the proteins that are attributed to Alzheimer's, but instead the condition can involve a mixture of interacting proteins from different neurodegenerative diseases.

"As a result, Alzheimer's should not be treated in isolation. According to these latest findings, pure, classical Alzheimer's disease, which involves only the attributed proteins tau and amyloid beta, appears not to be the norm," says Kovacs. There is also a varied regional distribution of nerve cell loss and protein deposits between patients which, taken together, have clinical prognostic significance. As a consequence of this, differentiated strategies need to be developed for personalised therapy that takes account of all the interacting factors.

The new treatment concepts which are currently being developed by the MedUni Vienna's neuropathologists, neurobiologists, neurologists, psychiatrists and neuroimaging experts will divide the patients into "sub-groups." Says Kovacs: "The aim is to define these groups very precisely in future in order to be able to offer them personalised treatment."

Dementia diseases: a growing trend

Around 100,000 Austrians are currently suffering from a dementia-related illness, according to statistics from the Austrian Alzheimer Society. According to estimates, this figure will rise to around 280,000 by 2050 as a result of the increasing age of the general population. Alzheimer's disease is responsible for 60 to 80 per cent of these conditions.

The global Alzheimer's report by "Alzheimer's Disease International" reckons that the prevalence of dementia doubles every 20 years. There are currently around 35 million people worldwide suffering a dementia-related illness. By 2030, their number will rise to 65.7 million and reach as many as 115.4 million by 2050.


Story Source:

The above story is based on materials provided by Medical University of Vienna. Note: Materials may be edited for content and length.


Cite This Page:

Medical University of Vienna. "'Foreign' proteins are also implicated in Alzheimer's disease." ScienceDaily. ScienceDaily, 21 September 2012. <www.sciencedaily.com/releases/2012/09/120921083154.htm>.
Medical University of Vienna. (2012, September 21). 'Foreign' proteins are also implicated in Alzheimer's disease. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2012/09/120921083154.htm
Medical University of Vienna. "'Foreign' proteins are also implicated in Alzheimer's disease." ScienceDaily. www.sciencedaily.com/releases/2012/09/120921083154.htm (accessed September 30, 2014).

Share This



More Mind & Brain News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Do Video Games Trump Brain Training For Cognitive Boosts?

Do Video Games Trump Brain Training For Cognitive Boosts?

Newsy (Sep. 29, 2014) More and more studies are showing positive benefits to playing video games, but the jury is still out on brain training programs. Video provided by Newsy
Powered by NewsLook.com
Your Spouse's Personality May Influence Your Earnings

Your Spouse's Personality May Influence Your Earnings

Newsy (Sep. 26, 2014) Research from Washington University suggest people with conscientious spouses have greater career success. Video provided by Newsy
Powered by NewsLook.com
Can A Blood Test Predict Psychosis Risk?

Can A Blood Test Predict Psychosis Risk?

Newsy (Sep. 26, 2014) Researchers say certain markers in the blood can predict risk of psychosis later in the life. The test can aid in early treatment for the condition. Video provided by Newsy
Powered by NewsLook.com
Harpist Soothes Gorillas, Orangutans With Music

Harpist Soothes Gorillas, Orangutans With Music

AP (Sep. 25, 2014) Teri Tacheny, a harpist, has a loyal following of fans who appreciate her soothing music. Every month, gorillas, orangutans and monkeys amble down to hear her play at the Como Park Zoo in Minnesota. (Sept. 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins