Featured Research

from universities, journals, and other organizations

Secrets in small blood vessels could reveal the risks of heart disease and diabetes

Date:
September 25, 2012
Source:
University of Southampton
Summary:
Researchers have embarked on a unique study that will shed new light on the risk of heart disease and diabetes in later life.

Researchers at the University of Southampton together with colleagues at King's College London have embarked on a unique study that will shed new light on the risk of heart disease and diabetes in later life.

Related Articles


A healthy diet for pregnant women is important for the health of the baby. Having a poor diet in pregnancy, such as one that is too high in fat, may cause problems in the offspring's later life. However, the exact mechanisms controlling the effect of diet during pregnancy on the long-term health of children are not well understood.

While other studies have investigated the impact of a mother's diet on the function of large blood vessels in her offspring, this study, led by Geraldine Clough, Professor of Vascular Physiology at the University of Southampton, is breaking new ground. By studying adult mouse offspring the researchers set out to investigate the effects of a high fat diet during a woman's pregnancy on the networks of small blood vessels -- called the microcirculation -- and to establish whether these networks are susceptible to damage from a poor maternal diet.

Professor Clough explains: "These small blood vessels, which are ten times smaller than a human hair, provide vital organs such as the heart, brain and muscles with important nutrients and oxygen. They are known to be altered in adult diseases such as obesity and diabetes but it is not known how they are influenced by maternal diet and so this work will give further insight into how an adverse high fat diet during pregnancy can increase the risk of adult disease in offspring.

"Secondly, since this microcirculation can be easily (and non-invasively) measured in humans then our study will inform us about how we can better use such measurements to give improved advice to children, mothers and women of child bearing age."

The study is being funded by the British Heart Foundation.

Dr Shannon Amoils, Research Advisor at the BHF, comments: "We're very pleased to announce this new research award of more than £100,000, which will help us gain a greater insight into how a child's health can be affected by their mother's diet during pregnancy.

"We know that if a mother eats a healthy diet during pregnancy, the benefits for her child can continue -- even into adulthood and middle age. This research in mice is looking at how the function of small blood vessels is affected by a poor maternal diet. This could help explain how eating poorly in pregnancy increases the risk of cardiovascular and metabolic disease, like high blood pressure and diabetes, in the offspring in later life."


Story Source:

The above story is based on materials provided by University of Southampton. Note: Materials may be edited for content and length.


Cite This Page:

University of Southampton. "Secrets in small blood vessels could reveal the risks of heart disease and diabetes." ScienceDaily. ScienceDaily, 25 September 2012. <www.sciencedaily.com/releases/2012/09/120925091546.htm>.
University of Southampton. (2012, September 25). Secrets in small blood vessels could reveal the risks of heart disease and diabetes. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2012/09/120925091546.htm
University of Southampton. "Secrets in small blood vessels could reveal the risks of heart disease and diabetes." ScienceDaily. www.sciencedaily.com/releases/2012/09/120925091546.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins