Featured Research

from universities, journals, and other organizations

Secrets in small blood vessels could reveal the risks of heart disease and diabetes

Date:
September 25, 2012
Source:
University of Southampton
Summary:
Researchers have embarked on a unique study that will shed new light on the risk of heart disease and diabetes in later life.

Researchers at the University of Southampton together with colleagues at King's College London have embarked on a unique study that will shed new light on the risk of heart disease and diabetes in later life.

Related Articles


A healthy diet for pregnant women is important for the health of the baby. Having a poor diet in pregnancy, such as one that is too high in fat, may cause problems in the offspring's later life. However, the exact mechanisms controlling the effect of diet during pregnancy on the long-term health of children are not well understood.

While other studies have investigated the impact of a mother's diet on the function of large blood vessels in her offspring, this study, led by Geraldine Clough, Professor of Vascular Physiology at the University of Southampton, is breaking new ground. By studying adult mouse offspring the researchers set out to investigate the effects of a high fat diet during a woman's pregnancy on the networks of small blood vessels -- called the microcirculation -- and to establish whether these networks are susceptible to damage from a poor maternal diet.

Professor Clough explains: "These small blood vessels, which are ten times smaller than a human hair, provide vital organs such as the heart, brain and muscles with important nutrients and oxygen. They are known to be altered in adult diseases such as obesity and diabetes but it is not known how they are influenced by maternal diet and so this work will give further insight into how an adverse high fat diet during pregnancy can increase the risk of adult disease in offspring.

"Secondly, since this microcirculation can be easily (and non-invasively) measured in humans then our study will inform us about how we can better use such measurements to give improved advice to children, mothers and women of child bearing age."

The study is being funded by the British Heart Foundation.

Dr Shannon Amoils, Research Advisor at the BHF, comments: "We're very pleased to announce this new research award of more than 100,000, which will help us gain a greater insight into how a child's health can be affected by their mother's diet during pregnancy.

"We know that if a mother eats a healthy diet during pregnancy, the benefits for her child can continue -- even into adulthood and middle age. This research in mice is looking at how the function of small blood vessels is affected by a poor maternal diet. This could help explain how eating poorly in pregnancy increases the risk of cardiovascular and metabolic disease, like high blood pressure and diabetes, in the offspring in later life."


Story Source:

The above story is based on materials provided by University of Southampton. Note: Materials may be edited for content and length.


Cite This Page:

University of Southampton. "Secrets in small blood vessels could reveal the risks of heart disease and diabetes." ScienceDaily. ScienceDaily, 25 September 2012. <www.sciencedaily.com/releases/2012/09/120925091546.htm>.
University of Southampton. (2012, September 25). Secrets in small blood vessels could reveal the risks of heart disease and diabetes. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2012/09/120925091546.htm
University of Southampton. "Secrets in small blood vessels could reveal the risks of heart disease and diabetes." ScienceDaily. www.sciencedaily.com/releases/2012/09/120925091546.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins