Featured Research

from universities, journals, and other organizations

Anemia negatively impacts heart surgery outcomes, study finds

Date:
October 1, 2012
Source:
Society of Thoracic Surgeons
Summary:
Anemia is now confirmed as a risk factor for illness and even death following cardiac surgery, according to a new study. Although preoperative anemia has been linked to adverse events in other types of surgery, this is the first study to tie preoperative anemia with postoperative complications, including death, for all types of heart surgery.

Anemia is now confirmed as a risk factor for illness and even death following cardiac surgery, according to a study published in the October 2012 issue of The Annals of Thoracic Surgery.

Related Articles


Although preoperative anemia has been linked to adverse events in other types of surgery, this is the first study to tie preoperative anemia with postoperative complications, including death, for all types of heart surgery.

Researchers from Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Donato in Milan, Italy, compared recorded medical outcomes for 401 adult cardiac surgery patients with severe anemia (hematocrit <30%) to 401 matched non-severely anemic heart surgery patients admitted to IRCCS between 2000 and 2011. They found that the patients with severe anemia had nearly double the operative mortality rate of patients who did not have severe anemia and were at increased risk for stroke, prolonged mechanical ventilation, and longer stays in the intensive care unit. Further investigation found similar results in patients with moderate anemia.

"Unlike other recognized risk factors for cardiac surgery patients, such as advanced age and poor kidney function, anemia can be corrected with iron supplementation and medications that stimulate red blood cell production," said lead author Marco Ranucci, MD. "Unfortunately, to correct anemia we need two to three weeks before the operation, which may be too long for many patients to wait."

Iron-deficiency anemia may result from blood loss, iron-poor diet, or insufficient iron absorption from food. Consequently, older adults are at risk for this common, easily treated anemia. Currently, preoperative anemia is not considered a risk factor for survival following heart surgery by the existing risk scores, although anemia's role had previously been investigated in outcomes for coronary artery bypass grafting (CABG) surgery.

"Until it can be clearly demonstrated that correcting anemia improves outcomes, I think that working to correct and preserve the natural hemoglobin in a patient's blood prior to surgery is a viable and safe option," Dr. Ranucci said.

Anemia should be identified in advance of heart surgery

In an invited commentary in the same issue, Jeremiah R. Brown, PhD, MS, an Assistant Professor at The Dartmouth Institute for Health Policy and Clinical Practice at the Geisel School of Medicine in Hanover, NH, wrote that the Ranucci paper presents a convincing case for adding severe anemia to current cardiac surgery preoperative mortality models and called on cardiothoracic societies in the US and Europe to evaluate existing models.

"Dr. Ranucci's work demonstrates that cardiac surgeons need to know about the preoperative presence of severe anemia when estimating the operative mortality risk," said Dr. Brown. "Doing so will provide patients with a more accurate estimate of operative risk than currently available in our risk models for informing surgeons and patients about the possible risks of surgery."

He added that certain diagnostic procedures could be planned well ahead of elective surgeries, such as CABG surgery, to help identify anemia and provide time to treat it. "This extra time would allow surgeons to review the results and determine a strategic plan," said Dr. Brown.


Story Source:

The above story is based on materials provided by Society of Thoracic Surgeons. Note: Materials may be edited for content and length.


Journal References:

  1. Marco Ranucci, Umberto Di Dedda, Serenella Castelvecchio, Lorenzo Menicanti, Alessandro Frigiola, Gabriele Pelissero. Impact of Preoperative Anemia on Outcome in Adult Cardiac Surgery: A Propensity-Matched Analysis. The Annals of Thoracic Surgery, 2012; 94 (4): 1134 DOI: 10.1016/j.athoracsur.2012.04.042
  2. Jeremiah R. Brown. Invited Commentary. The Annals of Thoracic Surgery, 2012; 94 (4): 1142 DOI: 10.1016/j.athoracsur.2012.04.065

Cite This Page:

Society of Thoracic Surgeons. "Anemia negatively impacts heart surgery outcomes, study finds." ScienceDaily. ScienceDaily, 1 October 2012. <www.sciencedaily.com/releases/2012/10/121001161234.htm>.
Society of Thoracic Surgeons. (2012, October 1). Anemia negatively impacts heart surgery outcomes, study finds. ScienceDaily. Retrieved November 20, 2014 from www.sciencedaily.com/releases/2012/10/121001161234.htm
Society of Thoracic Surgeons. "Anemia negatively impacts heart surgery outcomes, study finds." ScienceDaily. www.sciencedaily.com/releases/2012/10/121001161234.htm (accessed November 20, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN Says It Will Scale Up Its Ebola Response

UN Says It Will Scale Up Its Ebola Response

AFP (Nov. 20, 2014) UN Resident Coordinator David McLachlan-Karr and WHO representative in the country Daniel Kertesz updated the media on the UN Ebola response on Wednesday. Duration: 00:51 Video provided by AFP
Powered by NewsLook.com
Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Takata Offers "sincerest Condolences" To Victims of Malfunctioning Airbag

Reuters - US Online Video (Nov. 20, 2014) U.S. Congress hears from a victim and company officials as it holds a hearing on the safety of Takata airbags after reports of injuries. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Obesity Costs Almost As Much As War And Terrorism

Obesity Costs Almost As Much As War And Terrorism

Newsy (Nov. 20, 2014) The newest estimate of the cost of obesity is pretty jarring — $2 trillion. But how did researchers get to that number? Video provided by Newsy
Powered by NewsLook.com
Ebola Crisis Affecting US Adoptions

Ebola Crisis Affecting US Adoptions

AP (Nov. 20, 2014) The Sanborn family had hoped they'd be able to bring home their 5-year-old adopted son from Liberia by now. But Ebola has forced them to wait. The boy is just one of thousands of orphans in West Africa who've been impacted by the deadly virus. (Nov. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins