Featured Research

from universities, journals, and other organizations

Serious complications in people with type 1 diabetes and ongoing poor blood sugar control

Date:
October 2, 2012
Source:
Public Library of Science
Summary:
Strategies implemented in high-income countries to improve blood glucose control in people with type 1 diabetes and so reduce complications, such as heart attacks, strokes, and early death, are working, but there is much need for further improvement, according to a new study.

Strategies implemented in high-income countries to improve blood glucose control in people with type 1 diabetes and so reduce complications, such as heart attacks, strokes, and early death, are working, but there is much need for further improvement, according to a study from Scotland published in this week's PLOS Medicine.

Related Articles


Using information from national databases representing over 20 000 patients from 2005 to 2008, Scottish researchers led by Helen Colhoun from the University of Dundee, found that people with type 1 diabetes have 2 to 3 times the risk of heart attacks, strokes, or premature death than the general population and that this increased risk is higher in women than in men. The authors found that in those with type 1 diabetes, the risk (chance) of having a cardiovascular event (heart attack or stroke) for the first time was 2.5 higher in men and 3.2 higher in women, than in the general Scottish population. Furthermore, in those with type 1 diabetes, death rates from any cause were 2.6 higher in men and 2.7 higher in women than in the general Scottish population.

The authors also found a high number of deaths from coma in younger people with diabetes (caused by either an extremely high or an extremely low blood sugar level) and two to three extra deaths per 100 people a year in those aged 60 to 69 years with type 1 diabetes.

Worryingly, the authors also found that the majority of patients in this Scottish dataset had poorly controlled blood glucose levels, with only 13% having HbA1c levels (a test that measures the blood sugar control over the previous 3 months) in the target range. People with type 1 diabetes also had similar levels of smoking and of being overweight -- risk factors of cardiovascular disease -- as the general population.

The importance of tight blood sugar control for minimizing complications from diabetes has been understood for almost two decades. Therefore, there is an urgent need to understand why so few people with type 1 diabetes in settings such as that studied here have good control of their blood sugar, and what can be done to improve this situation.

The authors say: "Although the relative risks for cardiovascular disease and total mortality associated with type 1 diabetes in this population have declined relative to earlier studies, type 1 diabetes continues to be associated with higher cardiovascular disease and death rates than the non-diabetic population."

They continue: "A striking feature of the data is the very low rate of achievement of glycemic control targets."

The authors add: "Risk factor management should be improved to further reduce risk but better treatment approaches for achieving good glycaemic control are badly needed."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Shona J. Livingstone, Helen C. Looker, Eleanor J. Hothersall, Sarah H. Wild, Robert S. Lindsay, John Chalmers, Stephen Cleland, Graham P. Leese, John McKnight, Andrew D. Morris, Donald W. M. Pearson, Norman R. Peden, John R. Petrie, Sam Philip, Naveed Sattar, Frank Sullivan, Helen M. Colhoun. Risk of Cardiovascular Disease and Total Mortality in Adults with Type 1 Diabetes: Scottish Registry Linkage Study. PLoS Medicine, 2012; 9 (10): e1001321 DOI: 10.1371/journal.pmed.1001321

Cite This Page:

Public Library of Science. "Serious complications in people with type 1 diabetes and ongoing poor blood sugar control." ScienceDaily. ScienceDaily, 2 October 2012. <www.sciencedaily.com/releases/2012/10/121002171624.htm>.
Public Library of Science. (2012, October 2). Serious complications in people with type 1 diabetes and ongoing poor blood sugar control. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2012/10/121002171624.htm
Public Library of Science. "Serious complications in people with type 1 diabetes and ongoing poor blood sugar control." ScienceDaily. www.sciencedaily.com/releases/2012/10/121002171624.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins