Featured Research

from universities, journals, and other organizations

New research moves scientists closer to lung cancer blood test

Date:
October 15, 2012
Source:
University of York
Summary:
Early signs of lung cancer could be diagnosed using a simple blood test following a new discovery.

Early signs of lung cancer could be diagnosed using a simple blood test following a new discovery by scientists at the University of York.

Early detection of lung cancer has been shown to save lives, but available methods for screening at-risk people are either too costly or involve invasive procedures. The latest findings, published today in the Proceedings of the National Academy of Sciences, mean that a simple blood test could now be developed.

Dr Dawn Coverley, who is based at the University's Department of Biology and is funded by Yorkshire Cancer Research, has found that an altered form of a protein called Ciz1 is present in lung cancers, even when they are at a very early stage.

She said: "The Ciz1 protein is involved in cell growth and division. Altered forms of this protein are present in cancer cells, and one specific form is prevalent in lung cancers. Surprisingly, this variant-Ciz1 somehow gets into the blood stream and once there appears to be very stable. This means that by looking for variant Ciz1 in the blood we can pick out people who have small tumours in their lungs, without the need to take a biopsy or undergo surgery.

"We think that the test will be especially powerful when combined with X-ray or CT imaging, and will offer doctors an alternative way to test whether an abnormal growth is cancerous. For the patient, this means that many could avoid invasive diagnostic procedures altogether."

Kathryn Scott, Head of Research Funding for Yorkshire Cancer Research, said: "This research is related to a cancer which is prevalent in Yorkshire towns and cities. Lung cancer is very difficult to treat and has a low survival rate, but it is traditionally underfunded in the UK. Yorkshire Cancer Research is strongly committed to funding projects such as these, which have enormous potential patient benefit."

Cizzle Biotech, a spin out company from the University of York that is funded primarily by Yorkshire Cancer Research, the White Rose Seed Fund and Finance Yorkshire, is now translating the research into a test suitable for use in hospital diagnostic laboratories.


Story Source:

The above story is based on materials provided by University of York. Note: Materials may be edited for content and length.


Cite This Page:

University of York. "New research moves scientists closer to lung cancer blood test." ScienceDaily. ScienceDaily, 15 October 2012. <www.sciencedaily.com/releases/2012/10/121015151214.htm>.
University of York. (2012, October 15). New research moves scientists closer to lung cancer blood test. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2012/10/121015151214.htm
University of York. "New research moves scientists closer to lung cancer blood test." ScienceDaily. www.sciencedaily.com/releases/2012/10/121015151214.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Fungus Killing Bats, Spreading in US

Deadly Fungus Killing Bats, Spreading in US

AP (Apr. 24, 2014) A disease that has killed more than six million cave-dwelling bats in the United States is on the move and wildlife biologists are worried. White Nose Syndrome, discovered in New York in 2006, has now spread to 25 states. (April 24) Video provided by AP
Powered by NewsLook.com
Companies Ramp Up Wellness to Lower Health Costs

Companies Ramp Up Wellness to Lower Health Costs

AP (Apr. 24, 2014) That little voice telling you to exercise, get in shape and get healthy is probably coming from your boss. More companies are beefing up wellness programs to try and cut down their health care costs. (April 24) Video provided by AP
Powered by NewsLook.com
FDA Wants To Ban Sales Of E-Cigarettes To Minors

FDA Wants To Ban Sales Of E-Cigarettes To Minors

Newsy (Apr. 24, 2014) The Food and Drug Administration wants to crack down on the use of e-cigarettes, banning the sale of the product to minors. Video provided by Newsy
Powered by NewsLook.com
Michigan Man Sees Thanks to 'bionic Eye'

Michigan Man Sees Thanks to 'bionic Eye'

AP (Apr. 23, 2014) A legally blind Michigan man is 'seeing something new every day' thanks to a high-tech retinal implant procedure. He's one of the first in the country to receive a 'bionic eye' since the federal government approved the surgery. (April 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins