Featured Research

from universities, journals, and other organizations

Losing weight from either a low-carb or low-fat diet lowers body inflammation

Date:
November 5, 2012
Source:
Johns Hopkins Medicine
Summary:
When overweight or obese people lose weight, whether through a low-carb or low-fat diet, they can have a significant reduction in inflammation throughout their body, as measured by three common markers for inflammation.

A study by researchers at Johns Hopkins Medicine shows that when overweight or obese people lose weight, whether through a low-carb or low-fat diet, they can have a significant reduction in inflammation throughout their body, as measured by three common markers for inflammation.

Results of the study are being presented at the American Heart Association Scientific Sessions on November 5, 2012.

Inflammation occurs naturally when the body's immune system acts to fight off an irritant or infection or responds to an injury. However, fat cells secrete molecules that also increase inflammation, even when an immune response is not needed. Because these molecules are secreted into the bloodstream, being overweight or obese increases the risk of inflammation throughout the body. This more widespread condition is known as systemic inflammation.

According to the researchers, systemic inflammation increases the chance of a heart attack or stroke by promoting the formation of blood clots, interfering with the ability of blood vessels to contract and relax normally to control blood flow, or causing plaque to break off of vessel walls.

"Our findings indicate that you can reduce systemic inflammation, and possibly lower your risk of heart disease, no matter which diet -- either low-carb or low-fat," says Kerry Stewart, Ed.D., professor of medicine at the Johns Hopkins University School of Medicine and director of clinical and research exercise physiology. "The important factor is how much weight you lose -- especially belly fat."

Stewart adds that there's still some bias in the medical community against a low-carb diet, which, by definition has a higher percentage of fat and protein than a low-fat diet. In their study, 60 people, ages 30 to 65, who were either overweight or obese with excessive fat around their waist, were randomly assigned to go on a low-fat or a low-carb diet for six months. Each group also participated in exercise training three times a week.

The researchers measured the participants' blood levels for three common markers of inflammation -- C-reactive protein, interleukin 6 and tumor necrosis factor-alpha -- at the beginning and end of the study. They also measured body weight, body mass index (BMI) and total body and belly fat. At the start, both groups were similar in the various measures, including elevated levels of inflammation markers.

The participants on the low-carb diet lost more weight, on average, than those on the low-fat diet -- 28 pounds versus 18 pounds. The low-carb diet group also had a greater drop in BMI (4.7 versus 2.9), and a greater drop in belly fat (14.3 versus 8.4 pounds). The level of aerobic fitness increased in both groups by about 20 percent.

"In both groups, there was a significant drop in the levels of all three measures of inflammation," says Stewart, indicating that a diet higher in fat and protein doesn't interfere with the ability to lower inflammation, as long as you are losing weight.

The study was funded by the National Heart Lung and Blood Institute (NHLBI), part of the National Institutes of Health, under contract number R01HL092280.


Story Source:

The above story is based on materials provided by Johns Hopkins Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Johns Hopkins Medicine. "Losing weight from either a low-carb or low-fat diet lowers body inflammation." ScienceDaily. ScienceDaily, 5 November 2012. <www.sciencedaily.com/releases/2012/11/121105140038.htm>.
Johns Hopkins Medicine. (2012, November 5). Losing weight from either a low-carb or low-fat diet lowers body inflammation. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2012/11/121105140038.htm
Johns Hopkins Medicine. "Losing weight from either a low-carb or low-fat diet lowers body inflammation." ScienceDaily. www.sciencedaily.com/releases/2012/11/121105140038.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins