Featured Research

from universities, journals, and other organizations

CT depicts racial differences in coronary artery disease

Date:
November 28, 2012
Source:
Radiological Society of North America
Summary:
While obesity is considered a cardiovascular risk factor, a new study shows that African-American patients with coronary artery disease have much less fat around their hearts compared to Caucasian patients.

While obesity is considered a cardiovascular risk factor, a study presented November 28 at the annual meeting of the Radiological Society of North America (RSNA) showed that African-American patients with coronary artery disease (CAD) have much less fat around their hearts compared to Caucasian patients.

Related Articles


"Prior evidence suggests that increased fat around the heart may be either an independent marker of CAD burden or a predictor of the future risk of acute coronary events," said U. Joseph Schoepf, M.D., professor of radiology and medicine and director of cardiovascular imaging at the Medical University of South Carolina in Charleston, S.C. "You would think that African Americans, who have a higher prevalence of CAD, would have higher rates of thoracic fat in an acute chest pain setting. However, this was not the case. White patients had significantly higher thoracic fat volumes than African-American patients."

According to the Centers for Disease Control and Prevention, coronary heart disease is the leading cause of death for people of most ethnicities in the United States. In 2010, the age-adjusted prevalence of coronary heart disease was 6.5 percent among African Americans, compared to 5.8 percent among Caucasians.

"We were very interested in finding an explanation for the racial difference in CAD and suspected differences in thoracic adipose tissue between races might be one of the contributing factors," said Paul Apfaltrer, M.D., from the Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Heidelberg University, Germany.

For the study, researchers evaluated cardiac dual-source CT images of 411 age- and gender-matched African-American and Caucasian patients, quantifying thoracic fat volumes, including epicardial adipose tissue (EAT) -- body fat that is in direct contact with the heart -- and mediastinal adipose tissue, which is body fat within the chest cavity. Results showed that while the prevalence of significant stenosis, or narrowing of the coronary ducts, and plaque was similar in African-American and Caucasian patients, African-American patients had less fat around their hearts.

The findings, Drs. Schoepf and Apfaltrer say, are surprising, given the higher number of cardiac and metabolic disorders among African Americans despite presence of less fat in the chest cavity. The researchers suggest that EAT may actually act as a protective buffer, or that it may be related to plaque maturation including calcification, and could contribute to lower risk of acute coronary events.

"Understanding the mechanism behind the racial disparities we found may improve the prevention, risk stratification and management of CAD," Dr. Schoepf said.

Coauthors are John W. Nance Jr., M.D., Rozemarijn Vliegenthart, M.D., Ph.D., Mathias Meyer, B.Sc., Fabian Bamberg, M.D., M.P.H., and Andreas Schindler, B.S.


Story Source:

The above story is based on materials provided by Radiological Society of North America. Note: Materials may be edited for content and length.


Cite This Page:

Radiological Society of North America. "CT depicts racial differences in coronary artery disease." ScienceDaily. ScienceDaily, 28 November 2012. <www.sciencedaily.com/releases/2012/11/121128093802.htm>.
Radiological Society of North America. (2012, November 28). CT depicts racial differences in coronary artery disease. ScienceDaily. Retrieved November 22, 2014 from www.sciencedaily.com/releases/2012/11/121128093802.htm
Radiological Society of North America. "CT depicts racial differences in coronary artery disease." ScienceDaily. www.sciencedaily.com/releases/2012/11/121128093802.htm (accessed November 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, November 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins