Featured Research

from universities, journals, and other organizations

Better syringe designs could nearly eradicate global annual HIV infections from syringe sharing within eight years

Date:
January 16, 2013
Source:
RTI International
Summary:
Switching the type of syringe used by people who inject drugs could help curb HIV transmission in countries with injection-driven epidemics within eight years, according to a new article.

Low dead-space syringes could help reduce HIV transmission in countries with injection-driven epidemics.
Credit: Image courtesy of RTI International

Switching the type of syringe used by people who inject drugs could help curb HIV transmission in countries with injection-driven epidemics within eight years, according to a new article by researchers at RTI International and Futures Institute.

The commentary, published in the January issue of International Journal of Drug Policy (IJDP), summarizes existing evidence regarding how low dead-space syringes can help reduce HIV transmission and estimates potential impacts on HIV transmission among people who inject drugs.

According to the authors, when a plunger on a syringe is fully depressed, all syringes retain fluid in what has been termed "dead space." In high dead-space syringes, a 1000 times more blood is retained in the syringe after washing than in low dead-space syringes.

This suggests that if a person who injects drugs shares a high dead-space syringe with an HIV-positive injecting partner, they are more likely to be exposed to HIV than if he or she shared a low dead-space syringe.

Using a simulation model, the authors found that switching to low dead-space syringes could lead to major reductions in HIV transmission in countries with injection-driven epidemics, such as China, Indonesia, Russia, Ukraine and Vietnam. According to the model, the change could reduce annual HIV infections from syringe sharing to nearly zero within eight years.

"Although additional research is needed, this intervention should be implemented and evaluated as soon as possible," said William Zule, Dr.P.H., a senior research health analyst at RTI International and lead author of the paper. "Switching from high dead-space to low dead-space syringes should be viewed as an additional component to comprehensive HIV prevention packages."

Preventing or controlling concentrated HIV epidemics among persons who inject drugs may also prevent the sexual diffusion of HIV from people who inject drugs to other groups. "While the low dead-space syringe still requires testing in targeted populations and there remains considerable work to be done on its implementation, nevertheless we ought to welcome the emergence of a potentially effective new tool in the fight against HIV," said professor Gerry Stimson, director of Knowledge-Action-Change and editor of the IJDP.

The paper also describes potential obstacles to transitioning from high dead-space to low dead-space needles and syringes and presents strategies for overcoming these barriers. Among the reasons low dead-space syringes have not yet been considered a viable prevention intervention include limited awareness of how needle and syringe design influence HIV transmission and a general lack of information about low dead-space syringes.

"There are many difficulties related to scaling up effective HIV prevention programs in countries with HIV epidemics among persons who inject drugs," said Zule. "This is a comparatively simple and low-cost intervention that has the potential to be extremely effective."


Story Source:

The above story is based on materials provided by RTI International. Note: Materials may be edited for content and length.


Journal Reference:

  1. William A. Zule, Harry E. Cross, John Stover, Carel Pretorius. Low dead space syringes: Authors’ response. International Journal of Drug Policy, 2013; 24 (1): 21 DOI: 10.1016/j.drugpo.2012.11.003

Cite This Page:

RTI International. "Better syringe designs could nearly eradicate global annual HIV infections from syringe sharing within eight years." ScienceDaily. ScienceDaily, 16 January 2013. <www.sciencedaily.com/releases/2013/01/130116085949.htm>.
RTI International. (2013, January 16). Better syringe designs could nearly eradicate global annual HIV infections from syringe sharing within eight years. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2013/01/130116085949.htm
RTI International. "Better syringe designs could nearly eradicate global annual HIV infections from syringe sharing within eight years." ScienceDaily. www.sciencedaily.com/releases/2013/01/130116085949.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins