Featured Research

from universities, journals, and other organizations

AB blood type strong risk factor for venous blood clots

Date:
February 4, 2013
Source:
Canadian Medical Association Journal
Summary:
The non-O ABO blood type is the most important risk factor for venous thromboembolism (blood clots in veins), making up 20 percent of attributable risk for the condition, according to a new study.

The non-O ABO blood type is the most important risk factor for venous thromboembolism (blood clots in veins), making up 20% of attributable risk for the condition, according to a new study in CMAJ (Canadian Medical Association Journal).

Related Articles


This finding has implications for genetic screening for thrombophilia, a genetic predisposition to abnormal blood clotting.

Danish researchers looked at data on 66,001 people who had been followed for 33 years from 1977 through 2010 to determine whether ABO blood type is associated with an increased risk of venous blood clots in the general population. They found that the risk increased when ABO blood type was combined with factor V Leiden R506Q or prothrombin G20210A, genetic mutations associated with an increased risk of venous thromboembolisms. This finding confirms the conclusion of other studies. The researchers also found an 11-fold increased risk of venous thromboembolism for people with the prothrombin G20210A mutation in double dose, something other smaller trials did not pick up.

"We found an additive effect of ABO blood type on risk of venous thromboembolism when combined with factor V Leiden R506Q and prothrombin G20210A; ABO blood type was the most important risk factor for venous thromboembolism in the general population.," writes Dr. Børge G. Nordestgaard, Herlev Hospital, Copenhagen University Hospital with coauthors. "This suggests that ABO blood type should be included in genetic screening for thrombophilia."

The study was large, followed participants over a long period and follow up was 100% complete for participants. Although the study cohort was genetically homogenous compared with populations with ethnic diversity, the ABO blood type, factor V Leiden R506Q and prothrombin G20210A are found in all ethnicities.


Story Source:

The above story is based on materials provided by Canadian Medical Association Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. Birgitte F. Sode, Kristine H. Allin, Morten Dahl, Finn Gyntelberg, Børge G. Nordestgaard. Risk of venous thromboembolism and myocardial infarction associated with factor V Leiden and prothrombin mutations and blood type. CMAJ, 2013 DOI: 10.1503/cmaj.121636

Cite This Page:

Canadian Medical Association Journal. "AB blood type strong risk factor for venous blood clots." ScienceDaily. ScienceDaily, 4 February 2013. <www.sciencedaily.com/releases/2013/02/130204130034.htm>.
Canadian Medical Association Journal. (2013, February 4). AB blood type strong risk factor for venous blood clots. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2013/02/130204130034.htm
Canadian Medical Association Journal. "AB blood type strong risk factor for venous blood clots." ScienceDaily. www.sciencedaily.com/releases/2013/02/130204130034.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) — Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com
Ebola Fears Keep Guinea Hospitals Empty

Ebola Fears Keep Guinea Hospitals Empty

AP (Oct. 23, 2014) — Fears of Ebola are keeping doctors and patients alike away from hospitals in the West African nation of Guinea. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Despite Rising Death Toll, Many Survive Ebola

Despite Rising Death Toll, Many Survive Ebola

AP (Oct. 23, 2014) — The family of a Dallas nurse infected with Ebola in the US says doctors can no longer detect the virus in her. Despite the mounting death toll in West Africa, there are survivors there too. (Oct. 23) Video provided by AP
Powered by NewsLook.com
Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) — Is your child ready? Video provided by Working Mother
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins