Feb. 5, 2013 How, when and where a pathogen is transmitted between two individuals in a population is crucial in understanding and predicting how a disease will spread. New research has laid the foundation for a new generation of zoonotic disease spreading models, which could allow for more targeted prevention strategies.
By using novel complexity sciences tools the study, published in Physical Review Letters, outlines a predictive model of a spatial epidemic spread in a population of territorial animals.
By quantifying the instances of transmission events, the research team, Dr Luca Giuggioli, Senior Lecturer in Complexity Sciences in the Department of Engineering Mathematics and the School of Biological Sciences at the University of Bristol, and Dr David Sanders and Master's student, Sebastian Pérez-Becker, from UNAM, Mexico, have determined the propagation speed of a pathogen based on the knowledge of the demography of a species, the way animals wander and the degree of contagiousness of the disease.
As a large percentage of new and remerging human infectious diseases are of animal origin, models that track how pathogens hop from one animal host to another will help develop more effective control measures that are capable of identifying specific individuals or class of individuals rather than ineffective and costly widespread culling procedures of an entire population.
Dr Luca Giuggioli said: "The research findings have the potential to be applicable to various populations of territorial animals worldwide including in the UK bovine Tb in badgers, which has enormous economic implications for the cattle industry."
Bovine tuberculosis (Tb) in badgers, which affects cattle, the farming industry and has become a political issue, is an example of how the model could be used. Badgers are territorial animals and do transmit the infection by passing the bacterial pathogen to individuals in neighbouring territories, which is what the researchers have quantified in their model.
The research was funded by a grant from the Engineering and Physical Sciences Research Council (EPSRC) and the National Autonomous University of Mexico (UNAM), Mexico.
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- Luca Giuggioli, Sebastian Pérez-Becker, David P. Sanders. Encounter Times in Overlapping Domains: Application to Epidemic Spread in a Population of Territorial Animals. Physical Review Letters, 2013; 110 (5) DOI: 10.1103/PhysRevLett.110.058103
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