Featured Research

from universities, journals, and other organizations

Fruits and vegetables may help protect the kidneys

Date:
February 7, 2013
Source:
American Society of Nephrology (ASN)
Summary:
Adding fruits and vegetables to the diet is an effective alternative to medication to reduce metabolic acidosis and kidney injury in late-stage chronic kidney disease. Metabolic acidosis is a common complication of kidney disease.

Adding fruits and vegetables to the diet may help protect the kidneys of patients with chronic kidney disease (CKD) with too much acid build-up, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

Related Articles


Western diets that are based in animal and grain products are highly acidic and can lead to metabolic acidosis, when too much acid builds up in the body. This is particularly common in patients with CKD because the kidneys are responsible for removing acid through the urine. Metabolic acidosis can cause rapid breathing, confusion, and lethargy. Severe cases can lead to shock or death.

Alkali supplementation therapy such as bicarbonate is used to treat CKD patients with severe metabolic acidosis, but simply adding more fruits and vegetables -- which contain alkali -- to the diet might also help.

Nimrit Goraya, MD, Donald Wesson, MD (Texas A&M College of Medicine) and their colleagues tested this by randomizing 71 patients with hypertensive stage 4 CKD to receive added fruits and vegetables or an oral alkaline medication for one year. The treatments were dosed to decrease dietary acid by half.

Among the major findings:

• Kidney function was similar between the two groups after one year.

• One-year plasma total carbon dioxide (PTCO2) increased in both groups, which is consistent with a lessening of metabolic acidosis. PTCO2 was higher in patients receiving bicarbonate than in those receiving added fruits and vegetables.

• Urine measurements of kidney injury were lower after one year in both groups.

• Although fruits and vegetables are rich in potassium and might raise blood potassium to dangerous levels, levels did not increase in either group.

"We showed that by addition of alkali such as bicarbonate or alkali-inducing fruits and vegetables, patients had a favorable response by reduction of urinary kidney injury markers," said Dr. Wesson. "Our study suggests that these interventions will help maintain kidney health in those with kidney disease," added Dr. Goraya.

In an accompanying editorial, Muhammad Yaqoob, MD (Bartshealth NHS Trust and William Harvey Research Institute, in London) noted that the study is likely to have a limited impact on clinical practice. "A small group of highly motivated patients wishing to reduce their pill burden through dietary modification may benefit from the results of this study. However, many patients find it difficult to follow a diet high in fruits and vegetables and might therefore be more adherent to a supplement," he wrote. He added that a large multicenter randomized controlled trial examining the impact of supplemental bicarbonate, with and without dietary intervention, in patients with chronic kidney disease is urgently needed.

Study co-authors include Jan Simoni, PhD and Chan-Hee Jo, PhD.


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. N. Goraya, J. Simoni, C.-H. Jo, D. E. Wesson. A Comparison of Treating Metabolic Acidosis in CKD Stage 4 Hypertensive Kidney Disease with Fruits and Vegetables or Sodium Bicarbonate. Clinical Journal of the American Society of Nephrology, 2013; DOI: 10.2215/CJN.02430312

Cite This Page:

American Society of Nephrology (ASN). "Fruits and vegetables may help protect the kidneys." ScienceDaily. ScienceDaily, 7 February 2013. <www.sciencedaily.com/releases/2013/02/130207171737.htm>.
American Society of Nephrology (ASN). (2013, February 7). Fruits and vegetables may help protect the kidneys. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2013/02/130207171737.htm
American Society of Nephrology (ASN). "Fruits and vegetables may help protect the kidneys." ScienceDaily. www.sciencedaily.com/releases/2013/02/130207171737.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins