Featured Research

from universities, journals, and other organizations

Patients with diabetes at no greater risk for infection or other complications after total knee replacement

Date:
February 27, 2013
Source:
American Academy of Orthopaedic Surgeons
Summary:
Patients with diabetes were no more likely to suffer infection, deep vein thrombosis (a deep vein blood clot) or other complications following total knee replacement than patients without diabetes, according to new research.

Patients with diabetes were no more likely to suffer infection, deep vein thrombosis (a deep vein blood clot) or other complications following total knee replacement (TKR) than patients without diabetes, according to new research published onlineFebruary 27, in advance of its publication in the March 2013 Journal of Bone and Joint Surgery (JBJS).

Related Articles


The study authors sought to determine whether or not blood sugar level (glycemic control) influenced outcome in TKR. Fifty-two percent of people with diabetes have arthritis. Previous studies have found that poor glycemic control may cause postoperative complications.

Researchers reviewed records of more than 40,000 Kaiser Permanente patients who underwent TKR between January 2001 and December 2009, of whom 7,567 (18.7 percent) had diabetes, 464 underwent revision surgery (1.1 percent), and 287 (.7 percent) developed a deep infection. Of the total number of patients, 12.5 percent had controlled diabetes and 6.2 percent had uncontrolled diabetes.

In this study, researchers found no significant increase in risk for TKR revision, deep infection or deep vein thrombosis in patients with diabetes -- controlled or uncontrolled -- compared to patients without diabetes.

Other Key Findings:

  • Patients with diabetes were more likely than patients without diabetes to be obese (56.7 percent compared with 40.3 percent), and have a severe comorbidity (related disease/condition) burden (17.5 percent compared with 2.4 percent).
  • The rates of deep infection, deep vein thrombosis and pulmonary embolism (when a blood clot reaches the lungs) were low, and comparable in the controlled and uncontrolled diabetic groups to the non-diabetic group.
  • Uncontrolled diabetics did not appear to be associated with an increased risk of myocardial infarction (heart attack) or rehospitalization.
  • Controlled diabetics had a slightly greater percentage of revisions (1.7 percent) compared to uncontrolled diabetics (1.2 percent).

"This current study suggests that patients with diabetes who have higher glucose levels may not be at greater risk of poor surgical outcomes," said Annette L. Adams, PhD, MPH, of the Kaiser Permanente Southern California Department of Research & Evaluation. "There appear to be other factors at play, and patients and their providers need to consider multiple factors, including but not limited to diabetes status, as they make decisions about whether to have this surgery."


Story Source:

The above story is based on materials provided by American Academy of Orthopaedic Surgeons. Note: Materials may be edited for content and length.


Journal References:

  1. Annette L. Adams, Elizabeth W. Paxton, Jean Q. Wang, Eric S. Johnson, Elizabeth A. Bayliss, Assiamira Ferrara, Cynthia Nakasato, Stefano A. Bini, Robert S. Namba. Surgical Outcomes of Total Knee Replacement According to Diabetes Status and Glycemic Control, 2001 to 2009. The Journal of Bone and Joint Surgery (American), 2013; DOI: 10.2106/JBJS.L.00109
  2. Annette L. Adams. Surgical Outcomes of Total Knee Replacement According to Diabetes Status and Glycemic Control, 2001 to 2009. The Journal of Bone and Joint Surgery (American), 2013; DOI: 10.2106/JBJS.L.00109

Cite This Page:

American Academy of Orthopaedic Surgeons. "Patients with diabetes at no greater risk for infection or other complications after total knee replacement." ScienceDaily. ScienceDaily, 27 February 2013. <www.sciencedaily.com/releases/2013/02/130227134421.htm>.
American Academy of Orthopaedic Surgeons. (2013, February 27). Patients with diabetes at no greater risk for infection or other complications after total knee replacement. ScienceDaily. Retrieved April 19, 2015 from www.sciencedaily.com/releases/2013/02/130227134421.htm
American Academy of Orthopaedic Surgeons. "Patients with diabetes at no greater risk for infection or other complications after total knee replacement." ScienceDaily. www.sciencedaily.com/releases/2013/02/130227134421.htm (accessed April 19, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, April 19, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Dr. Oz Under Fire For 'Quack Treatments' Yet Again

Dr. Oz Under Fire For 'Quack Treatments' Yet Again

Newsy (Apr. 17, 2015) Ten doctors signed a letter urging Columbia University to drop Dr. Oz as vice chair of its department of surgery, saying he plugs "quack" treatments. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com
Video Messages Help Reassure Dementia Patients

Video Messages Help Reassure Dementia Patients

AP (Apr. 17, 2015) Family members are prerecording messages as part of a unique pilot program at the Hebrew Home in New York. The videos are trying to help victims of Alzheimer&apos;s disease and other forms of dementia break through the morning fog of forgetfulness. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins