Featured Research

from universities, journals, and other organizations

Shingles vaccine is associated with reduction in both postherpetic neuralgia and herpes zoster

Date:
April 9, 2013
Source:
Public Library of Science
Summary:
A vaccine to prevent shingles may reduce by half the occurrence of this painful skin and nerve infection in older people (aged over 65 years) and may also reduce the rate of a painful complication of shingles, post-herpetic neuralgia, but has a very low uptake (only 4 percent) in older adults in the United States, according to a new study.

Shingles vaccine is associated with reduction in both postherpetic neuralgia and herpes zoster, but uptake in the US is low.

A vaccine to prevent shingles may reduce by half the occurrence of this painful skin and nerve infection in older people (aged over 65 years) and may also reduce the rate of a painful complication of shingles, post-herpetic neuralgia, but has a very low uptake (only 4%) in older adults in the United States, according to a study by UK and US researchers published in this week's PLOS Medicine.

The researchers, led by Sinιad Langan from the London School of Hygiene and Tropical Medicine, reached these conclusions by examining the records of 766,330 Medicare beneficiaries* aged 65 years or more between 2007 and 2009.

They found that shingles vaccine uptake was extremely low -- only 3.9% of participants were vaccinated -- but was particularly low among black people (0.3%) and among people with a low income (0.6%).

Over the study period, almost 13,000 participants developed shingles and the vaccine reduced the rate of shingles by 48% (that is, approximately half as many vaccinated individuals developed shingles as those who were not vaccinated). However, the vaccine was less effective in older adults with impaired immune systems. The authors also found that vaccine effectiveness against post-herpetic neuralgia was 59%.

The authors say: "Herpes zoster vaccination was associated with a significant reduction in incident herpes zoster and [post-herpetic neuralgia] in routine clinical use."

They continue: "Despite strong evidence supporting its effectiveness, clinical use remains disappointingly low with particularly low vaccination rates in particular patient groups."

The authors add: " The findings are relevant beyond US medical practice, being of major importance to the many countries, including the UK, that are actively considering introducing the zoster vaccine into routine practice in the near future."


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Sinιad M. Langan, Liam Smeeth, David J. Margolis, Sara L. Thomas. Herpes Zoster Vaccine Effectiveness against Incident Herpes Zoster and Post-herpetic Neuralgia in an Older US Population: A Cohort Study. PLoS Medicine, 2013; 10 (4): e1001420 DOI: 10.1371/journal.pmed.1001420

Cite This Page:

Public Library of Science. "Shingles vaccine is associated with reduction in both postherpetic neuralgia and herpes zoster." ScienceDaily. ScienceDaily, 9 April 2013. <www.sciencedaily.com/releases/2013/04/130409173504.htm>.
Public Library of Science. (2013, April 9). Shingles vaccine is associated with reduction in both postherpetic neuralgia and herpes zoster. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2013/04/130409173504.htm
Public Library of Science. "Shingles vaccine is associated with reduction in both postherpetic neuralgia and herpes zoster." ScienceDaily. www.sciencedaily.com/releases/2013/04/130409173504.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) — A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
Google's Next Frontier: The Human Body

Google's Next Frontier: The Human Body

Newsy (July 27, 2014) — Google is collecting genetic and molecular information to paint a picture of the perfectly healthy human. Video provided by Newsy
Powered by NewsLook.com
What's To Blame For Worst Ebola Outbreak In History?

What's To Blame For Worst Ebola Outbreak In History?

Newsy (July 27, 2014) — A U.S. doctor has tested positive for the deadly Ebola virus, as the worst-ever outbreak continues to grow. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) — A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins