Featured Research

from universities, journals, and other organizations

Toward broad-spectrum antiviral drugs for common cold and other infections

Date:
June 26, 2013
Source:
American Chemical Society
Summary:
Scientists are reporting progress in the search for the first broad-spectrum drugs to combat human rhinoviruses, which cause humanity's most common infectious diseases.

Scientists are reporting progress in the search for the first broad-spectrum drugs to combat human rhinoviruses (HRVs), which cause humanity's most common infectious diseases.

Their study on these potential drugs for infections that include the common cold appears in the journal ACS Medicinal Chemistry Letters.

Angus MacLeod and colleagues note that although many HRV infections cause mild disease, they can lead to dangerous complications for millions of people with asthma and chronic obstructive pulmonary disease. Previous potential drugs for HRV either didn't work or caused unacceptable side effects, leaving only one potential drug still under development in clinical trials. MacLeod's team set out to find new antiviral candidates to meet this serious health challenge.

They describe identifying and successfully testing a group of compounds that work against human rhinovirus, Coxsackie virus, poliovirus and enterovirus-71 -- the cause of hand, foot and mouth disease. The substances work by blocking the ability of these viruses to multiply.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Angus M. MacLeod, Dale R. Mitchell, Nicholas J. Palmer, Hervι Van de Poλl, Katja Conrath, Martin Andrews, Pieter Leyssen, Johan Neyts. Identification of a Series of Compounds with Potent Antiviral Activity for the Treatment of Enterovirus Infections. ACS Medicinal Chemistry Letters, 2013; 130516102921008 DOI: 10.1021/ml400095m

Cite This Page:

American Chemical Society. "Toward broad-spectrum antiviral drugs for common cold and other infections." ScienceDaily. ScienceDaily, 26 June 2013. <www.sciencedaily.com/releases/2013/06/130626142942.htm>.
American Chemical Society. (2013, June 26). Toward broad-spectrum antiviral drugs for common cold and other infections. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2013/06/130626142942.htm
American Chemical Society. "Toward broad-spectrum antiviral drugs for common cold and other infections." ScienceDaily. www.sciencedaily.com/releases/2013/06/130626142942.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) — As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) — Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
U.S. Food Makers Surpass Calorie-Cutting Pledge

U.S. Food Makers Surpass Calorie-Cutting Pledge

Newsy (Sep. 18, 2014) — Sixteen large food and beverage companies in the United States that committed to cut calories in their products far surpassed their target. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) — Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins