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A maternal junk food diet alters development of opioid pathway in the offspring

Date:
July 30, 2013
Source:
Society for the Study of Ingestive Behavior
Summary:
New animal research suggests that maternal diet during pregnancy can alter the development of a signalling pathway associated with reward processing in the offspring.

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, shows that eating a junk-food diet during pregnancy changes the development of the opioid signalling pathway in the baby's brain and permanently alters the way this system operates after birth.

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Opioids are chemicals which are released when we eat foods that are high in fat and sugar, and that are responsible for causing the release of another 'feel good' chemical, dopamine. The researchers found that the gene encoding one of the key endogenous opioids, enkephalin, was expressed at a higher level in the offspring of mothers who had consumed a junk food diet than in the offspring of mothers who ate standard rat feed. This increase in enkephalin, together with previous work done by this research group which showed that an opioid receptor blocker was less effective at reducing fat and sugar intake in the pups of the junk-food fed mothers, provides evidence for the first time that the opioid signalling pathway is less sensitive in junk-food exposed offspring.

Being less sensitive to opioids means that individuals whose mothers eat excessive quantities of junk-food during pregnancy and breastfeeding, would have to eat more junk foods get the same 'feel good' response, and this would make them more likely to over consume these high-fat, high-sugar foods. Jessica Gugusheff from the FoodPlus research centre at the University of Adelaide, the graduate student leading this research, says that "the results of this studywill eventually permit us to better inform pregnant women about the enduring effect their diet has on the development of their child's lifelong food preferences and risk of negative metabolic outcomes."


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The above story is based on materials provided by Society for the Study of Ingestive Behavior. Note: Materials may be edited for content and length.


Cite This Page:

Society for the Study of Ingestive Behavior. "A maternal junk food diet alters development of opioid pathway in the offspring." ScienceDaily. ScienceDaily, 30 July 2013. <www.sciencedaily.com/releases/2013/07/130730091407.htm>.
Society for the Study of Ingestive Behavior. (2013, July 30). A maternal junk food diet alters development of opioid pathway in the offspring. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2013/07/130730091407.htm
Society for the Study of Ingestive Behavior. "A maternal junk food diet alters development of opioid pathway in the offspring." ScienceDaily. www.sciencedaily.com/releases/2013/07/130730091407.htm (accessed November 28, 2014).

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