Featured Research

from universities, journals, and other organizations

Genesis and evolution of H7N9 influenza virus

Date:
August 21, 2013
Source:
NIH/National Institute of Allergy and Infectious Diseases
Summary:
Influenza researchers have used genetic sequencing to trace the source and evolution of the avian H7N9 influenza virus that emerged in humans in China earlier this year.

An international team of influenza researchers in China, the United Kingdom and the United States has used genetic sequencing to trace the source and evolution of the avian H7N9 influenza virus that emerged in humans in China earlier this year. The study, published today in Nature, was supported by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health, and other organizations.

Working in three Chinese provinces, researchers led by Yi Guan, Ph.D., of the University of Hong Kong collected samples from the throats and digestive tracts of chickens, ducks, geese, pigeons and quail. Fecal and water samples from live poultry markets and the natural environment were also collected. From these samples, the researchers isolated several influenza viruses and genetically sequenced those of the H7N9 subtype as well as related H7N7 and H9N2 viruses.

These sequences were compared with archived sequences of the same subtypes isolated in southern China between 2000 and 2013. The researchers compared the differences between the two sets of sequences to reconstruct how the H7N9 virus evolved through various species of birds and to determine the origin of genes.

According to their analysis, domestic ducks and chickens played distinct roles in the genesis of the H7N9 virus infecting humans today. Within ducks, and later within chickens, various strains of avian H7N9, H7N7 and H9N2 influenza exchanged genes with one another in different combinations. The resulting H7N9 virus began causing outbreaks among chickens in live poultry markets, from which many humans became infected. Given these results, the authors write, continued surveillance of influenza viruses in birds remains essential.


Story Source:

The above story is based on materials provided by NIH/National Institute of Allergy and Infectious Diseases. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tommy Tsan-Yuk Lam, Jia Wang, Yongyi Shen, Boping Zhou, Lian Duan, Chung-Lam Cheung, Chi Ma, Samantha J. Lycett, Connie Yin-Hung Leung, Xinchun Chen, Lifeng Li, Wenshan Hong, Yujuan Chai, Linlin Zhou, Huyi Liang, Zhihua Ou, Yongmei Liu, Amber Farooqui, David J. Kelvin, Leo L. M. Poon, David K. Smith, Oliver G. Pybus, Gabriel M. Leung, Yuelong Shu, Robert G. Webster, Richard J. Webby, Joseph S. M. Peiris, Andrew Rambaut, Huachen Zhu, Yi Guan. The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature, 2013; DOI: 10.1038/nature12515

Cite This Page:

NIH/National Institute of Allergy and Infectious Diseases. "Genesis and evolution of H7N9 influenza virus." ScienceDaily. ScienceDaily, 21 August 2013. <www.sciencedaily.com/releases/2013/08/130821132734.htm>.
NIH/National Institute of Allergy and Infectious Diseases. (2013, August 21). Genesis and evolution of H7N9 influenza virus. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2013/08/130821132734.htm
NIH/National Institute of Allergy and Infectious Diseases. "Genesis and evolution of H7N9 influenza virus." ScienceDaily. www.sciencedaily.com/releases/2013/08/130821132734.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins