Featured Research

from universities, journals, and other organizations

Low inflammation may explain healthy metabolic status in some obese people

Date:
August 27, 2013
Source:
Endocrine Society
Summary:
Reduced levels of inflammation may explain how some obese people are able to remain metabolically healthy, according to a recent study.

Reduced levels of inflammation may explain how some obese people are able to remain metabolically healthy, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Obesity generally is linked to a higher risk of diabetes and heart disease. Some people who are obese, however, do not develop high blood pressure and unfavorable cholesterol profiles -- factors that increase the risk of metabolic diseases. This phenomenon is described as metabolically healthy obesity. Although estimates vary widely, as much as 35 percent of the obese population may be metabolically healthy.

"In our study, metabolically healthy people -- both obese and non-obese -- had lower levels of a range of inflammatory markers," said the study's lead author, Catherine Phillips, BSc, PhD, of University College Cork in Ireland. "Regardless of their body mass index, people with favorable inflammatory profiles also tended to have healthy metabolic profiles."

The cross-sectional study was conducted between 2010 and 2011 at a large primary care center in Mitchelstown, County Cork, Ireland. Researchers analyzed data from 2,040 participants in the Cork and Kerry Diabetes and Heart Disease Study (Phase II). Participants, who were between the ages of 50 and 69, completed lifestyle questionnaires, physical and clinical assessments, and underwent blood testing so their body mass index (BMI), metabolic profiles and inflammatory markers could be determined.

Researchers examined levels of several inflammatory markers. People who were metabolically healthy had reduced counts of white blood cells and acute-phase response proteins, which proliferate when inflammation occurs. Metabolically healthy people also had higher levels of adiponectin, a hormone that has an anti-inflammatory effect, compared to their metabolically unhealthy counterparts. Researchers found this inflammatory profile in both obese and lean people who were metabolically healthy.

"From a public health standpoint, we need better methods for identifying which obese people face the greatest risk of diabetes and heart disease," Phillips said. "Inflammatory markers offer a potential strategy for pinpointing people who could benefit most from medical interventions."

Professor Ivan Perry of University College Cork also worked on the study, which was funded by the Irish Health Research Board.

The article, "Does Inflammation Determine Metabolic Health Status in Obese and Non-Obese Adults," will be published in the October issue of JCEM.


Story Source:

The above story is based on materials provided by Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

Endocrine Society. "Low inflammation may explain healthy metabolic status in some obese people." ScienceDaily. ScienceDaily, 27 August 2013. <www.sciencedaily.com/releases/2013/08/130827134746.htm>.
Endocrine Society. (2013, August 27). Low inflammation may explain healthy metabolic status in some obese people. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2013/08/130827134746.htm
Endocrine Society. "Low inflammation may explain healthy metabolic status in some obese people." ScienceDaily. www.sciencedaily.com/releases/2013/08/130827134746.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins