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Combination therapies a cost-effective alternative for treating visceral leishmaniasis

Date:
September 16, 2013
Source:
Institute of Tropical Medicine Antwerp
Summary:
Visceral leishmaniasis is the second-deadliest parasitic disease after malaria. Each year, thousands fall victim among poor and marginalised populations in low-income countries. A new study is the first to detail the economic aspects of the disease in India, Nepal and Sudan.

Visceral leishmaniasis is the second-deadliest parasitic disease after malaria. Each year, thousands fall victim among poor and marginalised populations in low-income countries. Filip Meheus is the first to detail the economic aspects of the disease in India, Nepal and Sudan. On 16 September, Meheus will receive a PhD title at the University of Nijmegen for his research at the Institute of Tropical Medicine (ITM) in Antwerp.

Visceral leishmaniasis has become harder to control, because current treatments increasingly fail (like in Nepal with resistance to the drug miltefosine). Meheus shows that combination therapies (the use of multiple drugs) is a cost-effective alternative to the current first-line treatments. This is mainly due to the shorter duration of treatment and the lower cost of the drugs used for combination therapies.

Combination therapies would also alleviate the enormous economic damage the disease causes in families and relieve the workload in hospitals. However, additional efforts are needed to further drop prices of some drugs (like liposomal amphotericin B) and diagnose and treat patients more quickly.

"This disease wrecks patients twice, both physically and financially. The study results offer tools to assist them better, even where the needs are huge and the means limited," said Meheus.

The full study can be accessed here: http://www.itg.be/internet/dl/EconomicAnalysisOfVLControl-FilipMeheus.pdf


Story Source:

The above story is based on materials provided by Institute of Tropical Medicine Antwerp. Note: Materials may be edited for content and length.


Cite This Page:

Institute of Tropical Medicine Antwerp. "Combination therapies a cost-effective alternative for treating visceral leishmaniasis." ScienceDaily. ScienceDaily, 16 September 2013. <www.sciencedaily.com/releases/2013/09/130916090842.htm>.
Institute of Tropical Medicine Antwerp. (2013, September 16). Combination therapies a cost-effective alternative for treating visceral leishmaniasis. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2013/09/130916090842.htm
Institute of Tropical Medicine Antwerp. "Combination therapies a cost-effective alternative for treating visceral leishmaniasis." ScienceDaily. www.sciencedaily.com/releases/2013/09/130916090842.htm (accessed July 30, 2014).

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