Featured Research

from universities, journals, and other organizations

Inhaled corticosteroids raise pneumonia risk

Date:
September 18, 2013
Source:
University of Alberta
Summary:
Use of inhaled corticosteroids leads to twofold risk of repeat pneumonia among older populations, according to results of a new study.

A University of Alberta researcher says health professionals should be cautious about prescribing inhaled corticosteroids to high-risk patients such as pneumonia survivors, citing a twofold risk for repeat infection.

Dean Eurich led a research team that examined inhaled corticosteroid use among elderly patients for a clinical study. The team evaluated more than 6,200 seniors who survived an initial episode of pneumonia but were still at high risk of developing another bout of infection.

Over the five-year study, 653 seniors had a repeat episode -- and inhaled corticosteroid use was associated with a 90 per cent increase in risk for these repeat occurrences compared with the rate among those not using the drugs.

"Given the evidence starting to emerge on inhaled corticosteroids, health professionals have to use their own clinical judgement to try and determine which patients should remain on the drugs, especially for patients with pneumonia," said Eurich, an associate professor in the School of Public Health and trained pharmacist.

Inhaled corticosteroids are used to treat asthma and chronic obstructive pulmonary disease -- chronic bronchitis and emphysema -- as well as other respiratory disorders such as a nagging cough. Several smaller studies have examined the risk of developing pneumonia, but the U of A team is the first to look at such a large group of high-risk seniors.

More research is needed as to why these drugs pose a greater pneumonia risk, but for patients taking them, Eurich has healthy advice: listen to your health professional, wash your hands often and get vaccinated to reduce your risk of respiratory infections.

"Continue on your medications as your health professional has told you to use them. If you're feeling unwell, if you are coughing or wheezing more, are more short of breath than usual, have chest pain when breathing deeply or coughing, feel fatigued, or develop a fever, see a physician sooner rather than later."

Research begins at bedside

Eurich says the new findings would not have been possible without talented collaborators such as Alberta Diabetes Institute colleague Sumit Majumdar of the Faculty of Medicine & Dentistry and the faculty's former dean, Tom Marrie, now at Dalhousie University, as well as data and support from Alberta Health and Alberta Health Services.

"When we set up this cohort, there was a ton of support from the University of Alberta and because there's such a good relationship between the university and the health system, it easily facilitated our work," he said. "When researchers have access to data for population-based studies, we can look at safety issues with medications in real-world patients."

The research was published last month in the peer-reviewed journal Clinical Infectious Diseases.


Story Source:

The above story is based on materials provided by University of Alberta. Note: Materials may be edited for content and length.


Journal Reference:

  1. D. T. Eurich, C. Lee, T. J. Marrie, S. R. Majumdar. Inhaled Corticosteroids and Risk of Recurrent Pneumonia: A Population-Based, Nested Case-Control Study. Clinical Infectious Diseases, 2013; DOI: 10.1093/cid/cit472

Cite This Page:

University of Alberta. "Inhaled corticosteroids raise pneumonia risk." ScienceDaily. ScienceDaily, 18 September 2013. <www.sciencedaily.com/releases/2013/09/130918130650.htm>.
University of Alberta. (2013, September 18). Inhaled corticosteroids raise pneumonia risk. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2013/09/130918130650.htm
University of Alberta. "Inhaled corticosteroids raise pneumonia risk." ScienceDaily. www.sciencedaily.com/releases/2013/09/130918130650.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins