Featured Research

from universities, journals, and other organizations

Physical activity may reduce risk of esophageal cancer

Date:
October 14, 2013
Source:
American College of Gastroenterology (ACG)
Summary:
Physical activity is associated with a reduced risk of esophageal cancer, particularly esophageal adenocarcinoma, according to a new meta-analysis of published observational studies.

Physical activity is associated with a reduced risk of esophageal cancer, particularly esophageal adenocarcinoma, according to a new meta-analysis of published observational studies presented by Mayo Clinic researcher Siddharth Singh, M.D., at the American College of Gastroenterology's 78th Annual Scientific Meeting in San Diego, CA.

In a meta-analysis of four studies, Dr. Singh and his colleagues observed a 32 percent lower risk of esophageal adenocarcinoma, which can arise from Barrett's esophagus, in people who were physically active. The meta-analysis also showed the overall risk of esophageal cancer was 19 percent lower among the most physically active people, compared with the least physically active.

"Obesity has been associated with increased risk of esophageal cancer through high levels of insulin, as well as chronic inflammation. By decreasing visceral fat, lowering the level of carcinogenic adipokines, improving insulin sensitivity, and decreasing chronic inflammation, physical activity can potentially decrease risk of esophageal cancer," said Dr. Singh.

Esophageal cancer is the sixth most common cancer in men worldwide, and has a dismal five-year survival rate of approximately 15 percent, with most patients dying within the first year of diagnosis. There are two types of esophageal cancer: esophageal squamous cell, which begins in cells lining the esophagus, and adenocarcinoma, which begins in cells that make and release mucus and other fluids. Dr. Singh and colleagues note that although, "the incidence of esophageal squamous cell cancer is declining worldwide, the incidence of esophageal adenocarcinoma has been rapidly rising. This increase may be partly attributable to the obesity epidemic."

Current evidence for this link has been limited to observational studies. According to Dr. Singh it is too early to conclude that exercise directly decreases esophageal cancer risk. He proposes that physically active people may be more likely to take preventive health measures, as compared to patients who are not physically active. Thus, he says, it is possible that other healthy lifestyle behaviors aside from physical activity contribute to a lower cancer risk.

There are ongoing randomized controlled trials assessing the effect of exercise on esophageal cancer risk in patients with Barrett's esophagus.


Story Source:

The above story is based on materials provided by American College of Gastroenterology (ACG). Note: Materials may be edited for content and length.


Cite This Page:

American College of Gastroenterology (ACG). "Physical activity may reduce risk of esophageal cancer." ScienceDaily. ScienceDaily, 14 October 2013. <www.sciencedaily.com/releases/2013/10/131014093533.htm>.
American College of Gastroenterology (ACG). (2013, October 14). Physical activity may reduce risk of esophageal cancer. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2013/10/131014093533.htm
American College of Gastroenterology (ACG). "Physical activity may reduce risk of esophageal cancer." ScienceDaily. www.sciencedaily.com/releases/2013/10/131014093533.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



    Save/Print:
    Share:

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile: iPhone Android Web
    Follow: Facebook Twitter Google+
    Subscribe: RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins