Featured Research

from universities, journals, and other organizations

Antibiotic use for catheter-associated bacteriuria futile in decreasing mortality

Date:
October 16, 2013
Source:
Society for Healthcare Epidemiology of America
Summary:
Many patients with indwelling urinary catheters acquire bacteria in the urinary tract while they are catheterized. Most previous studies assessing morbidity and mortality associated with catheter use have not separated urinary tract infection from asymptomatic bacteriuria. This has made it difficult to determine if bacteria in the urine puts patients at higher risk for bloodstream infection or death.

With 30 million indwelling bladder catheters placed annually nationwide, patients face an increased risk of developing catheter-associated bacteriuria (bacteria in the urine). Many patients with indwelling urinary catheters acquire bacteria in the urinary tract while they are catheterized. Most previous studies assessing morbidity and mortality associated with catheter use have not separated urinary tract infection from asymptomatic bacteriuria. This has made it difficult to determine if bacteria in the urine puts patients at higher risk for bloodstream infection or death. The study is published in the November issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

Related Articles


In a retrospective cohort study of 444 urine cultures from 308 patients, researchers at Baylor College of Medicine found that catheter-associated urinary tract infection, but not asymptomatic bacteriuria, was significantly associated with developing bacteremia (bacteria in the bloodstream) within 30 days but was not significantly associated with mortality. Treatment with antibiotics did not reduce the risk of developing bacteremia or change mortality rates.

Overall mortality was high (21.1 percent), indicating, as expected, that hospitalized patients who require indwelling bladder catheters have many serious underlying illnesses.

"Our study findings call into question what we are accomplishing by treating with antibiotics bacteria that are found in urine in asymptomatic patients" said Barbara Trautner, MD, senior author of the study.

Fifty-two patients experienced bacteria in the bloodstream within a month after the urine culture was collected, but only three of these infections might have started in the urinary tract. In other words, only three of 444 positive urine cultures (less than 1%) might have led to bloodstream infection. Giving antimicrobial agents specifically to treat bacteria found in the urine did not decrease the risk of bloodstream infection or death. In spite of that, nearly 90 percent of patients (277 of 308 patients) received some antimicrobial agent for some reason, not necessarily to treat the urine, between 7 days before to 30 days after obtaining the urine culture.


Story Source:

The above story is based on materials provided by Society for Healthcare Epidemiology of America. Note: Materials may be edited for content and length.


Journal Reference:

  1. Quratulain F. Kizilbash, Nancy J. Petersen, Guoqing J. Chen, Aanand D. Naik, Barbara W. Trautner. Bacteremia and Mortality with Urinary Catheter–Associated Bacteriuria. Infection Control and Hospital Epidemiology, 2013; 34 (11): 1153 DOI: 10.1086/673456

Cite This Page:

Society for Healthcare Epidemiology of America. "Antibiotic use for catheter-associated bacteriuria futile in decreasing mortality." ScienceDaily. ScienceDaily, 16 October 2013. <www.sciencedaily.com/releases/2013/10/131016100430.htm>.
Society for Healthcare Epidemiology of America. (2013, October 16). Antibiotic use for catheter-associated bacteriuria futile in decreasing mortality. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2013/10/131016100430.htm
Society for Healthcare Epidemiology of America. "Antibiotic use for catheter-associated bacteriuria futile in decreasing mortality." ScienceDaily. www.sciencedaily.com/releases/2013/10/131016100430.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins