Featured Research

from universities, journals, and other organizations

Reduced need for joint surgery in patients with rheumatoid arthritis over time

Date:
October 27, 2013
Source:
American College of Rheumatology (ACR)
Summary:
Treating rheumatoid arthritis patients with intensive pharmacological agents, such as biologic drugs, may reduce the need for orthopedic joint surgery, according to new research.

Treating rheumatoid arthritis patients with intensive pharmacological agents, such as biologic drugs, may reduce the need for orthopedic joint surgery, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

Related Articles


Rheumatoid arthritis is a chronic disease that causes pain, stiffness, swelling, and limitation in the motion and function of multiple joints. Though joints are the principal body parts affected by RA, inflammation can develop in other organs as well. An estimated 1.3 million Americans have RA, and the disease typically affects women twice as often as men.

Researchers based in Malmφ, Sweden, looked at the incidence of any type of orthopedic joint surgery performed in Sweden on a total of 2,342 people with RA who fulfilled the 1987 ACR criteria for the disease. Of these, 68.7 percent were female. Patients drawn from RA patient registries from the years 1997, 2002, 2005 and 2009, were sent questionnaires to assess their general health and pain levels. Between 62 and 74 percent of RA patients contacted responded to the survey. Patient questionnaire responses were linked to the Swedish national health registry records to correlate the data with records of inpatient and outpatient surgeries, as well as use of biologic drugs. The incidence rate of orthopedic joint surgeries in this population from 1998 to 2001 was compared to the rates in the 2002 to 2006 and 2007 to 2011 time periods.

The researchers conducted the study to determine "whether the incidence of orthopaedic surgery is declining over time in patients with RA, and whether patient-reported outcomes predict the need for such procedures in future," according to Korosh Hekmat, MD; specialist in internal medicine rheumatology and PhD fellow; Malmφ University; and the lead author on the study.

Incidence of all orthopedic surgeries for RA patients from 1998 to 2011 was 82.3 out of 1,000 people, but the researchers noticed significant declines over the time periods studied. In the 1998 to 2001 time period, there was a 94.6 incidence rate, while in the 2007 to 2011 time period, there was a 71.8 incidence rate. Decreases were noted in both large joint (hips) and small joint (hands, wrists, feet and ankles) surgeries. Knee surgeries did not show a decline. Factors that increased the incidence of joint surgery were female gender and a higher rate of disability according to standard Health Assessment Questionnaire scores.

The time period studied coincided with increased use of early pharmacologic intervention in RA cases, especially with biologic drugs, although the researchers did not confirm the patients were using these drugs. Using these drugs early in the RA disease process may help halt inflammation and the joint erosion it can cause, thus preventing the need for orthopedic surgery the study's authors concluded.

"Our study suggests that the rate of orthopedic surgery was reduced by early intensive treatment in patients with severe RA," says Dr. Hekmat. Patients should talk to their rheumatologists to determine their best course of treatment.


Story Source:

The above story is based on materials provided by American College of Rheumatology (ACR). Note: Materials may be edited for content and length.


Cite This Page:

American College of Rheumatology (ACR). "Reduced need for joint surgery in patients with rheumatoid arthritis over time." ScienceDaily. ScienceDaily, 27 October 2013. <www.sciencedaily.com/releases/2013/10/131027122921.htm>.
American College of Rheumatology (ACR). (2013, October 27). Reduced need for joint surgery in patients with rheumatoid arthritis over time. ScienceDaily. Retrieved January 29, 2015 from www.sciencedaily.com/releases/2013/10/131027122921.htm
American College of Rheumatology (ACR). "Reduced need for joint surgery in patients with rheumatoid arthritis over time." ScienceDaily. www.sciencedaily.com/releases/2013/10/131027122921.htm (accessed January 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, January 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Oxfam Calls for Massive Aid for Ebola-Hit West Africa

Oxfam Calls for Massive Aid for Ebola-Hit West Africa

AFP (Jan. 29, 2015) — Oxfam International has called for a multi-million dollar post-Ebola "Marshall Plan", with financial support given by wealthy countries, to help Guinea, Sierra Leone and Liberia to recover. Duration: 01:10 Video provided by AFP
Powered by NewsLook.com
Are We Winning The Fight Against Ebola?

Are We Winning The Fight Against Ebola?

Newsy (Jan. 29, 2015) — The World Health Organization announced the fight against Ebola has entered its second phase as the number of cases per week has steadily dropped. Video provided by Newsy
Powered by NewsLook.com
Calif. Health Officials Campaign Against E-Cigarettes

Calif. Health Officials Campaign Against E-Cigarettes

Newsy (Jan. 29, 2015) — The California Health Department says e-cigarettes are a public health risk for both smokers and those who inhale e-cig smoke secondhand. Video provided by Newsy
Powered by NewsLook.com
Measles Scare Sends 66 Calif. Students Home

Measles Scare Sends 66 Calif. Students Home

AP (Jan. 29, 2015) — Officials say 66 students at a Southern California high school have been told to stay home through the end of next week because they may have been exposed to measles and are not vaccinated. (Jan. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins