Featured Research

from universities, journals, and other organizations

New test may predict severe high blood pressure during pregnancy

Date:
November 4, 2013
Source:
American Heart Association
Summary:
A new test that checks the level of a placental protein could help doctors determine if a woman will develop a severe form of high blood pressure during pregnancy.

A new test that checks the level of a placental protein could help doctors determine if a woman will develop a severe form of high blood pressure during pregnancy, according to a study in the American Heart Association journal Circulation.

High blood pressure affects 6 percent to 8 percent of pregnant women in the United States, according to the National Heart, Lung, and Blood Institute.

Preeclampsia is a complex form of high blood pressure in pregnancy that can damage the kidneys, liver and brain and lead to fetal complications such as premature delivery, low birth weight and stillbirth.

“The test is designed to differentiate women with preeclampsia from those with high blood pressure alone,” said Lucy Chappell, Ph.D., clinical senior lecturer in Obstetrics at King’s College in London. “Current tests for the condition only detect that it’s happening, rather than predicting it, and by that time the disease has progressed and has likely already caused organ damage.

“The test identifies women at high risk for developing preeclampsia, so doctors can better monitor and treat the blood pressure. It also prevents unnecessary hospitalizations of those who are not likely to develop preeclampsia.”

The study included 625 patients from various centers in the United Kingdom, of which 61 percent developed preeclampsia.

Women in the study with low levels of the protein placental growth factor (PlGF) developed preeclampsia. If protein levels were less than 100 pg/mL at less than 35 weeks of pregnancy, the baby was likely delivered within 14 days, researchers said. In a normal pregnancy, the level of placental growth factor is 100-3,000 pg/mL and doesn’t decrease.

“I would propose that further assessment of PlGF should be undertaken to measure the impact of changing diagnostic and treatment decisions on the health of mother and baby,” Chappell said.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. L. C. Chappell, S. Duckworth, P. T. Seed, M. Griffin, J. Myers, L. Mackillop, N. Simpson, J. Waugh, D. Anumba, L. C. Kenny, C. W. G. Redman, A. H. Shennan. Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia: A Prospective Multicenter Study. Circulation, 2013; 128 (19): 2121 DOI: 10.1161/CIRCULATIONAHA.113.003215

Cite This Page:

American Heart Association. "New test may predict severe high blood pressure during pregnancy." ScienceDaily. ScienceDaily, 4 November 2013. <www.sciencedaily.com/releases/2013/11/131104152624.htm>.
American Heart Association. (2013, November 4). New test may predict severe high blood pressure during pregnancy. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2013/11/131104152624.htm
American Heart Association. "New test may predict severe high blood pressure during pregnancy." ScienceDaily. www.sciencedaily.com/releases/2013/11/131104152624.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins