Featured Research

from universities, journals, and other organizations

New test may predict severe high blood pressure during pregnancy

Date:
November 4, 2013
Source:
American Heart Association
Summary:
A new test that checks the level of a placental protein could help doctors determine if a woman will develop a severe form of high blood pressure during pregnancy.

A new test that checks the level of a placental protein could help doctors determine if a woman will develop a severe form of high blood pressure during pregnancy, according to a study in the American Heart Association journal Circulation.

High blood pressure affects 6 percent to 8 percent of pregnant women in the United States, according to the National Heart, Lung, and Blood Institute.

Preeclampsia is a complex form of high blood pressure in pregnancy that can damage the kidneys, liver and brain and lead to fetal complications such as premature delivery, low birth weight and stillbirth.

“The test is designed to differentiate women with preeclampsia from those with high blood pressure alone,” said Lucy Chappell, Ph.D., clinical senior lecturer in Obstetrics at King’s College in London. “Current tests for the condition only detect that it’s happening, rather than predicting it, and by that time the disease has progressed and has likely already caused organ damage.

“The test identifies women at high risk for developing preeclampsia, so doctors can better monitor and treat the blood pressure. It also prevents unnecessary hospitalizations of those who are not likely to develop preeclampsia.”

The study included 625 patients from various centers in the United Kingdom, of which 61 percent developed preeclampsia.

Women in the study with low levels of the protein placental growth factor (PlGF) developed preeclampsia. If protein levels were less than 100 pg/mL at less than 35 weeks of pregnancy, the baby was likely delivered within 14 days, researchers said. In a normal pregnancy, the level of placental growth factor is 100-3,000 pg/mL and doesn’t decrease.

“I would propose that further assessment of PlGF should be undertaken to measure the impact of changing diagnostic and treatment decisions on the health of mother and baby,” Chappell said.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. L. C. Chappell, S. Duckworth, P. T. Seed, M. Griffin, J. Myers, L. Mackillop, N. Simpson, J. Waugh, D. Anumba, L. C. Kenny, C. W. G. Redman, A. H. Shennan. Diagnostic Accuracy of Placental Growth Factor in Women With Suspected Preeclampsia: A Prospective Multicenter Study. Circulation, 2013; 128 (19): 2121 DOI: 10.1161/CIRCULATIONAHA.113.003215

Cite This Page:

American Heart Association. "New test may predict severe high blood pressure during pregnancy." ScienceDaily. ScienceDaily, 4 November 2013. <www.sciencedaily.com/releases/2013/11/131104152624.htm>.
American Heart Association. (2013, November 4). New test may predict severe high blood pressure during pregnancy. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2013/11/131104152624.htm
American Heart Association. "New test may predict severe high blood pressure during pregnancy." ScienceDaily. www.sciencedaily.com/releases/2013/11/131104152624.htm (accessed April 16, 2014).

Share This



More Health & Medicine News

Wednesday, April 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Outbreak Now Linked To 121 Deaths

Ebola Outbreak Now Linked To 121 Deaths

Newsy (Apr. 15, 2014) The ebola virus outbreak in West Africa is now linked to 121 deaths. Health officials fear the virus will continue to spread in urban areas. Video provided by Newsy
Powered by NewsLook.com
Cognitive Function: Is It All Downhill From Age 24?

Cognitive Function: Is It All Downhill From Age 24?

Newsy (Apr. 15, 2014) A new study out of Canada says cognitive motor performance begins deteriorating around age 24. Video provided by Newsy
Powered by NewsLook.com
How Mt. Everest Helped Scientists Research Diabetes

How Mt. Everest Helped Scientists Research Diabetes

Newsy (Apr. 15, 2014) British researchers were able to use Mount Everest's low altitudes to study insulin resistance. They hope to find ways to treat diabetes. Video provided by Newsy
Powered by NewsLook.com
Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Carpenter's Injury Leads To Hundreds Of 3-D-Printed Hands

Newsy (Apr. 14, 2014) Richard van As lost all fingers on his right hand in a woodworking accident. Now, he's used the incident to create a prosthetic to help hundreds. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins