Featured Research

from universities, journals, and other organizations

Newly identified brown fat stem cells hold possibilities for treating diabetes, obesity

Date:
November 21, 2013
Source:
University of Utah Health Sciences
Summary:
The recent identification of brown fat stem cells in adult humans may lead to new treatments for heart and endocrine disorders, according to a new study.

Obesity and diabetes have become a global epidemic leading to severe cardiovascular disease. Researchers at the University of Utah believe their recent identification of brown fat stem cells in adult humans may lead to new treatments for heart and endocrine disorders, according to a new study published in the peer-reviewed journal Stem Cells.

The study was led by Amit N. Patel, M.D. M.S., director of Clinical Regenerative Medicine and Tissue Engineering and associate professor in the Division of Cardiothoracic Surgery at the University of Utah School of Medicine.

Prior to Patel's study, it was thought that brown fat stem cells did not exist in adults. Children have large amounts of brown fat that is highly metabolically active, which allows them to eat large amounts of food and not gain weight. Patel notes, adults generally have an abundance of white fat in their bodies, which leads to weight gain and cardiovascular disease but this is not seen in brown fat. As people age the amount of white fat increases and brown fat decreases which contributes to diabetes and high cholesterol.

"If you have more brown fat, you weigh less, you're metabolically efficient, and you have fewer instances of diabetes and high cholesterol. The unique identification of human brown fat stem cells in the chest of patients aged from 28 to 84 years is profound. We were able to isolate the human stem cells, culture and grow them, and implant them into a pre-human model which has demonstrated positive effects on glucose levels," said Patel.

The new discovery of finding brown fat stem cells may help in identifying potential drugs that may increase the body's own ability to make brown fat or find novel ways to directly implant the brown fat stem cells into patients.

The current study will be presented November 22nd at the Annual Meeting of the International Federation for Adipose Therapeutics and Science (iFATS) in New York City. The study was sponsored in part by BioRestorative Therapies, Inc. (Jupiter, Florida.)


Story Source:

The above story is based on materials provided by University of Utah Health Sciences. Note: Materials may be edited for content and length.


Journal Reference:

  1. Francisco J Silva, Dolly J Holt, Vanessa Vargas, James Yockman, Sihem Boudina, Donald Atkinson, David W Grainger, Monica P Revelo, Warren Sherman, David A Bull, Amit N Patel. Metabolically active human brown adipose tissue derived stem cells. STEM CELLS, 2013; DOI: 10.1002/stem.1595

Cite This Page:

University of Utah Health Sciences. "Newly identified brown fat stem cells hold possibilities for treating diabetes, obesity." ScienceDaily. ScienceDaily, 21 November 2013. <www.sciencedaily.com/releases/2013/11/131121125655.htm>.
University of Utah Health Sciences. (2013, November 21). Newly identified brown fat stem cells hold possibilities for treating diabetes, obesity. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2013/11/131121125655.htm
University of Utah Health Sciences. "Newly identified brown fat stem cells hold possibilities for treating diabetes, obesity." ScienceDaily. www.sciencedaily.com/releases/2013/11/131121125655.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins