Featured Research

from universities, journals, and other organizations

Short-term energy deficits increase factors related to muscle degradation

Date:
December 2, 2013
Source:
Federation of American Societies for Experimental Biology
Summary:
Building upon the discovery that a high-protein diet reduces muscle loss when dieting, a new research report now helps explain why. Protein consumption slows the ubiquitin proteasome system, which is primarily responsible for degrading skeletal muscle.

Building upon the discovery that a high-protein diet reduces muscle loss when dieting, a new research report published online in The FASEB Journal now helps explain why. Protein consumption slows the ubiquitin proteasome system, which is primarily responsible for degrading skeletal muscle.

"Reductions in muscle mass are often an unintended consequence of weight loss, and can have negative health consequences," said Stefan M. Pasiakos, Ph.D., study author from the Military Nutrition Division at the US Army Research Institute of Environmental Medicine in Natick, MA. "It is our hope that the findings from this well-controlled study will significantly contribute to the development of nutritional interventions designed to aid in the preservation of muscle mass during weight loss."

Pasiakos and colleagues assigned young men and women controlled diets for 31 days that provided dietary protein at three different levels: 1) Institute of Medicine's (IOM) RDA, 2) twice IOM's RDA, and 3) three times IOM's RDA. Volunteers were given adequate total calories to maintain constant body weight for the first 10 days to allow their metabolism to adapt to the dietary protein level. For the next 21 days, weight loss was induced by restricting the total calories consumed and increasing daily exercise to elicit an average two pound weight loss per week. Study measures were collected in the fasted state and following consumption of a protein-containing mixed-meal, at the end of both the stable weight maintenance and weight loss phases of the study. All meals were prepared and administered by research staff and exercise was highly controlled and supervised.

"A lot of diets and fitness programs focus on losing weight without regard to the type of weight you are losing, whether it be fat, muscle or water," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Fortunately, it appears that by simply having a high protein intake, you can minimize the amount of muscle you lose during your weight loss effort."


Story Source:

The above story is based on materials provided by Federation of American Societies for Experimental Biology. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. W. Carbone, L. M. Margolis, J. P. McClung, J. J. Cao, N. E. Murphy, E. R. Sauter, G. F. Combs, A. J. Young, S. M. Pasiakos. Effects of energy deficit, dietary protein, and feeding on intracellular regulators of skeletal muscle proteolysis. The FASEB Journal, 2013; 27 (12): 5104 DOI: 10.1096/fj.13-239228

Cite This Page:

Federation of American Societies for Experimental Biology. "Short-term energy deficits increase factors related to muscle degradation." ScienceDaily. ScienceDaily, 2 December 2013. <www.sciencedaily.com/releases/2013/12/131202142733.htm>.
Federation of American Societies for Experimental Biology. (2013, December 2). Short-term energy deficits increase factors related to muscle degradation. ScienceDaily. Retrieved April 19, 2014 from www.sciencedaily.com/releases/2013/12/131202142733.htm
Federation of American Societies for Experimental Biology. "Short-term energy deficits increase factors related to muscle degradation." ScienceDaily. www.sciencedaily.com/releases/2013/12/131202142733.htm (accessed April 19, 2014).

Share This



More Health & Medicine News

Saturday, April 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com
Obama: 8 Million Healthcare Signups

Obama: 8 Million Healthcare Signups

AP (Apr. 17, 2014) President Barack Obama gave a briefing Thursday announcing 8 million people have signed up under the Affordable Care Act. He blasted continued Republican efforts to repeal the law. (April 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins