Featured Research

from universities, journals, and other organizations

Study shows elevated rates of inadequate pap tests in transgender men

Date:
January 15, 2014
Source:
Springer Science+Business Media
Summary:
Cervical cancer can still occur in female-to-male transgender men. A new study finds that female-to-male (FTM) transgender patients had over 10 times higher odds of having an inadequate Papanicolaou (Pap) test compared to female patients.

A new study finds that female-to-male (FTM) transgender patients had over 10 times higher odds of having an inadequate Papanicolaou (Pap) test compared to female patients. The findings, by Fenway Health's Jennifer Potter, MD, and colleagues at Fenway, Harvard Medical School and the Johns Hopkins School of Public Health, appear in the Journal of General Internal Medicine, published by Springer.

The researchers found that FTM patients were more likely to have an inadequate Pap, with prevalence of inadequate samples 8.3 times higher among tests of FTM patients (10.8% vs. 1.3% of tests); were more likely to have had multiple inadequate Pap tests; and had longer latency to follow-up testing. Time on testosterone therapy was also independently associated with, but did not fully account for, Pap inadequacy.

Cervical cancer can still occur in FTM transgender men, the majority of whom do not undergo complete sex reassignment surgery or undergo total hysterectomy later in life. Because of this, national guidelines recommend that transgender men with a cervix follow the same screening protocol as non-transgender females.

This study points to the need to better understand and address possible reasons for Pap inadequacy among FTM patients, including cytological changes induced by testosterone and patient/provider discomfort with the pelvic exam.. In addition, alternatives to repeated Pap testing, such as cytologic reprocessing of inadequate samples or primary HPV DNA screening should be studied for efficacy and acceptability among FTM patients.

"Pap tests are important for FTM patients but it can be challenging to obtain interpretable results," said Dr. Potter, Director of Women's Health at Fenway Health. "More information is needed on the effects of testosterone on the cervix and effective cervical screening strategies that do not rely on a Pap test. While we wait for results of studies that address these questions clinicians should do everything possible to increase patient comfort during the exam and alert FTM patients that repeat Pap testing may be necessary after an initial, inadequate result."

This retrospective electronic medical record review study analyzed results of Pap tests performed on 233 FTM and 3625 female patients at an urban community health center between 2006 and 2012.


Story Source:

The above story is based on materials provided by Springer Science+Business Media. Note: Materials may be edited for content and length.


Journal Reference:

  1. Sarah M. Peitzmeier, Sari L. Reisner, Padmini Harigopal, Jennifer Potter. Female-to-Male Patients Have High Prevalence of Unsatisfactory Paps Compared to Non-Transgender Females: Implications for Cervical Cancer Screening. Journal of General Internal Medicine, 2014; DOI: 10.1007/s11606-013-2753-1

Cite This Page:

Springer Science+Business Media. "Study shows elevated rates of inadequate pap tests in transgender men." ScienceDaily. ScienceDaily, 15 January 2014. <www.sciencedaily.com/releases/2014/01/140115113036.htm>.
Springer Science+Business Media. (2014, January 15). Study shows elevated rates of inadequate pap tests in transgender men. ScienceDaily. Retrieved September 18, 2014 from www.sciencedaily.com/releases/2014/01/140115113036.htm
Springer Science+Business Media. "Study shows elevated rates of inadequate pap tests in transgender men." ScienceDaily. www.sciencedaily.com/releases/2014/01/140115113036.htm (accessed September 18, 2014).

Share This



More Health & Medicine News

Thursday, September 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins