Featured Research

from universities, journals, and other organizations

Low vitamin D levels during pregnancy may increase risk of severe preeclampsia

Date:
January 27, 2014
Source:
University of Pittsburgh Schools of the Health Sciences
Summary:
Women who are deficient in vitamin D in the first 26 weeks of their pregnancy may be at risk of developing severe preeclampsia, a potentially life-threatening disorder diagnosed by an increase in blood pressure and protein in the urine, according to research.

Women who are deficient in vitamin D in the first 26 weeks of their pregnancy may be at risk of developing severe preeclampsia, a potentially life-threatening disorder diagnosed by an increase in blood pressure and protein in the urine, according to research by the University of Pittsburgh Graduate School of Public Health.

In one of the largest studies to date, researchers studied blood samples collected from 700 pregnant women who later developed preeclampsia in an effort to examine a woman's vitamin D status during pregnancy and her risk of developing preeclampsia. The full study, funded by the National Institutes of Health (NIH), is available online in the journal Epidemiology, and will publish in the March print issue.

"For decades, vitamin D was known as a nutrient that was important only for bone health," said lead author Lisa Bodnar, Ph.D., M.P.H., R.D., associate professor in Pitt Public Health's Department of Epidemiology. "Over the past 10 to 15 years, scientists have learned that vitamin D has diverse functions in the body beyond maintaining the skeleton, including actions that may be important for maintaining a healthy pregnancy."

Dr. Bodnar and her colleagues also studied blood samples from 3,000 mothers who did not develop preeclampsia. The samples were collected between 1959 and 1965 at 12 U.S. sites enrolled in the Collaborative Perinatal Project. The blood was well-preserved, and researchers were able to test for vitamin D levels decades later.

Scientists controlled for factors that could have affected a woman's vitamin D status, including race, pre-pregnancy body mass index, number of previous pregnancies, smoking, diet, physical activity and sunlight exposure, which is the body's primary source of vitamin D.

The researchers found that vitamin D sufficiency was associated with a 40 percent reduction in risk of severe preeclampsia. But there was no relationship between vitamin D and mild preeclampsia. The overall risk of severe preeclampsia in the women sampled was 0.6 percent, regardless of vitamin D status.

"Scientists believe that severe preeclampsia and mild preeclampsia have different root causes," said senior author Mark A. Klebanoff, M.D., M.P.H., Center for Perinatal Research at The Research Institute at Nationwide Children's Hospital and the Department of Pediatrics at The Ohio State University College of Medicine. "Severe preeclampsia poses much higher health risks to the mother and child, so linking it with a factor that we can easily treat, like vitamin D deficiency, holds great potential."

"If our results hold true in a modern sample of pregnant women, then further exploring the role of vitamin D in reducing the risk of preeclampsia would be warranted," said Dr. Bodnar. "Until then, women shouldn't automatically take vitamin D supplements during pregnancy as a result of these findings."


Story Source:

The above story is based on materials provided by University of Pittsburgh Schools of the Health Sciences. Note: Materials may be edited for content and length.


Journal Reference:

  1. Lisa M. Bodnar, Hyagriv N. Simhan, Janet M. Catov, James M. Roberts, Robert W. Platt, Jill C. Diesel, Mark A. Klebanoff. Maternal Vitamin D Status and the Risk of Mild and Severe Preeclampsia. Epidemiology, 2014; 1 DOI: 10.1097/EDE.0000000000000039

Cite This Page:

University of Pittsburgh Schools of the Health Sciences. "Low vitamin D levels during pregnancy may increase risk of severe preeclampsia." ScienceDaily. ScienceDaily, 27 January 2014. <www.sciencedaily.com/releases/2014/01/140127141900.htm>.
University of Pittsburgh Schools of the Health Sciences. (2014, January 27). Low vitamin D levels during pregnancy may increase risk of severe preeclampsia. ScienceDaily. Retrieved April 24, 2014 from www.sciencedaily.com/releases/2014/01/140127141900.htm
University of Pittsburgh Schools of the Health Sciences. "Low vitamin D levels during pregnancy may increase risk of severe preeclampsia." ScienceDaily. www.sciencedaily.com/releases/2014/01/140127141900.htm (accessed April 24, 2014).

Share This



More Health & Medicine News

Thursday, April 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Big Pharma Braces for M&A Wave

Big Pharma Braces for M&A Wave

Reuters - Business Video Online (Apr. 22, 2014) Big pharma on the move as Novartis boss, Joe Jimenez, tells Reuters about plans to transform his company via an asset exchange with GSK, and Astra Zeneca shares surge on speculation that Pfizer is looking for a takeover. Joanna Partridge reports. Video provided by Reuters
Powered by NewsLook.com
Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
Hagel Gets Preview of New High-Tech Projects

Hagel Gets Preview of New High-Tech Projects

AP (Apr. 22, 2014) Defense Secretary Chuck Hagel is given hands-on demonstrations Tuesday of some of the newest research from DARPA _ the military's Defense Advanced Research Projects Agency program. (April 22) Video provided by AP
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins