Featured Research

from universities, journals, and other organizations

Excess weight linked to brain changes that may relate to memory, emotions, and appetite

Date:
February 11, 2014
Source:
SUNY Downstate Medical Center
Summary:
Being overweight appears related to reduced levels of a molecule that reflects brain cell health in the hippocampus, a part of the brain involved in memory, learning, and emotions, and likely also involved in appetite control, according to a new study.

Being overweight appears related to reduced levels of a molecule that reflects brain cell health in the hippocampus, a part of the brain involved in memory, learning, and emotions, and likely also involved in appetite control, according to a new study.
Credit: Discovod / Fotolia

Being overweight appears related to reduced levels of a molecule that reflects brain cell health in the hippocampus, a part of the brain involved in memory, learning, and emotions, and likely also involved in appetite control, according to a study performed by researchers at SUNY Downstate Medical Center and other institutions. The results of the study were published in Neuroimage: Clinical.

Related Articles


Jeremy D. Coplan, MD, professor of psychiatry at SUNY Downstate, led a multicenter team that visualized the molecule, N-acetyl-aspartate (NAA), using magnetic resonance spectroscopy, a non-invasive magnetic resonance imaging (MRI) application. NAA is associated with brain cell health. Overweight study participants exhibited lower levels of NAA in the hippocampus than normal weight subjects. The effect was independent of age, sex, and psychiatric diagnoses.

The importance of the hippocampus -- a seahorse-shaped organ deep within the brain -- to the formation and preservation of memory and to emotional control is well known, Dr. Coplan notes, but its role in appetite control is less established.

"The relevance of the finding is that being overweight is associated with specific changes in a part of the brain that is crucial to memory formation and emotions, and probably to appetite," said Dr. Coplan. The study is believed to be the first human research documenting the association of NAA with body weight.

"Whether low NAA is a consequence of being overweight, causes being overweight, or a combination of both remains to be determined," Dr. Coplan added. "Future studies are planned to focus on whether weight loss leads to an increase in NAA."

"We also found that high worry also produced low levels of NAA in the hippocampus, but was not associated with a high body mass index (BMI)," Dr. Coplan said. Dr. Coplan and his team looked at persons with a BMI equal to or greater than 25. Normal weight is defined as a BMI of 18.5-24.9, overweight between 25 and 29.9, and obesity at a BMI of 30 or greater.


Story Source:

The above story is based on materials provided by SUNY Downstate Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jeremy D. Coplan, Hassan M. Fathy, Chadi G. Abdallah, Sherif A. Ragab, John G. Kral, Xiangling Mao, Dikoma C. Shungu, Sanjay J. Mathew. Reduced hippocampal N-acetyl-aspartate (NAA) as a biomarker for overweight. NeuroImage: Clinical, 2014; 4: 326 DOI: 10.1016/j.nicl.2013.12.014

Cite This Page:

SUNY Downstate Medical Center. "Excess weight linked to brain changes that may relate to memory, emotions, and appetite." ScienceDaily. ScienceDaily, 11 February 2014. <www.sciencedaily.com/releases/2014/02/140211121829.htm>.
SUNY Downstate Medical Center. (2014, February 11). Excess weight linked to brain changes that may relate to memory, emotions, and appetite. ScienceDaily. Retrieved November 27, 2014 from www.sciencedaily.com/releases/2014/02/140211121829.htm
SUNY Downstate Medical Center. "Excess weight linked to brain changes that may relate to memory, emotions, and appetite." ScienceDaily. www.sciencedaily.com/releases/2014/02/140211121829.htm (accessed November 27, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, November 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins