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Sleep apnea may contribute to fatigue in multiple sclerosis: Study

Date:
February 14, 2014
Source:
American Academy of Sleep Medicine
Summary:
A new study provides evidence that obstructive sleep apnea (OSA) is highly prevalent in people with multiple sclerosis (MS), and it suggests that OSA may be a contributor to the fatigue that is one of the most common and debilitating symptoms of MS.

A new study provides evidence that obstructive sleep apnea (OSA) is highly prevalent in people with multiple sclerosis (MS), and it suggests that OSA may be a contributor to the fatigue that is one of the most common and debilitating symptoms of MS.

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Results show that one-fifth of MS patients surveyed in a large tertiary MS practice carried a diagnosis of OSA, and more than half were found to have an elevated risk for OSA based on a validated screening tool. Further analysis showed that OSA risk was a significant predictor of fatigue severity, even after adjusting for potential confounders such as age, gender, body mass index (BMI), sleep duration and depression.

"OSA may be a highly prevalent and yet under-recognized contributor to fatigue in persons with MS," said lead author and principal investigator Tiffany J. Braley, MD, MS, an Assistant Professor of Neurology from the University of Michigan Multiple Sclerosis and Sleep Disorders Centers in Ann Arbor, Mich. "Our study suggests that clinicians should have a low threshold to evaluate MS patients for underlying sleep disturbances."

The study results appear in the Feb. 15 issue of the Journal of Clinical Sleep Medicine, which is published by the American Academy of Sleep Medicine.

"Obstructive sleep apnea is a chronic illness that can have a destructive impact on your health and quality of life," said American Academy of Sleep Medicine President Dr. M. Safwan Badr. "People with multiple sclerosis who are found to have a high risk of OSA should be referred to a board certified sleep medicine physician for a comprehensive sleep evaluation."

Braley and her colleagues, Benjamin M. Segal, MD (Director of the University of Michigan Multiple Sclerosis Center), and Ronald D. Chervin, MD, MS, (Director of the University of Michigan Sleep Disorders Center) studied 195 MS patients who completed a sleep questionnaire and four validated instruments designed to assess daytime sleepiness, fatigue severity, insomnia severity and OSA risk. Medical records also were accessed to examine clinical characteristics that may predict fatigue or OSA risk.

According to the authors, the cross-sectional design of the study did not allow for an examination of cause-and-effect relationships. However, the results suggest that a substantial portion of MS-related fatigue could be eliminated by the diagnosis and successful treatment of OSA in patients with MS.


Story Source:

The above story is based on materials provided by American Academy of Sleep Medicine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Tiffany J. Braley, Benjamin M. Segal, Ronald D. Chervin. Obstructive Sleep Apnea and Fatigue in Patients with Multiple Sclerosis. Journal of Clinical Sleep Medicine, 2014; DOI: 10.5664/jcsm.3442

Cite This Page:

American Academy of Sleep Medicine. "Sleep apnea may contribute to fatigue in multiple sclerosis: Study." ScienceDaily. ScienceDaily, 14 February 2014. <www.sciencedaily.com/releases/2014/02/140214152042.htm>.
American Academy of Sleep Medicine. (2014, February 14). Sleep apnea may contribute to fatigue in multiple sclerosis: Study. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2014/02/140214152042.htm
American Academy of Sleep Medicine. "Sleep apnea may contribute to fatigue in multiple sclerosis: Study." ScienceDaily. www.sciencedaily.com/releases/2014/02/140214152042.htm (accessed November 28, 2014).

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