Featured Research

from universities, journals, and other organizations

Traffic-related air pollution associated with changes in right ventricular structure, function

Date:
March 7, 2014
Source:
American Thoracic Society (ATS)
Summary:
Exposure to high levels of traffic-related air pollution is associated with changes in the right ventricle of the heart that may contribute to the known connection between air pollution exposure and heart disease, according to a new study. “The morphologic changes in the right ventricle of the heart that we found with increased exposure to nitrogen dioxide add to the body of evidence supporting a connection between traffic-related air pollution and cardiovascular disease,” said the lead author. “The many adverse effects of air pollution on human health support continued efforts to reduce this burden.”

Exposure to high levels of traffic-related air pollution is associated with changes in the right ventricle of the heart that may contribute to the known connection between air pollution exposure and heart disease, according to a new study.

Related Articles


“Although the link between traffic-related air pollution and left ventricular hypertrophy, heart failure, and cardiovascular death is established, the effects of traffic-related air pollution on the right ventricle have not been well studied,” said lead author Peter Leary, MD, MS, of the University of Washington Medical Center in Seattle. “Using exposure to nitrogen dioxide as a surrogate for exposure to traffic-related air pollution, we were able to demonstrate for the first time that higher levels of exposure were associated with greater right ventricular mass and larger right ventricular end-diastolic volume. Greater right ventricular mass is also associated with increased risk for heart failure and cardiovascular death.”

The findings were published online ahead of print publication in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

The study involved 3,896 participants who were free of clinical cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis and who underwent cardiac magnetic resonance imaging (MRI). Using estimated exposure to outdoor oxides of nitrogen at the homes of participants over the year preceding MRI, the authors found that increased exposure to nitrogen dioxide was associated with an approximately 1.0 g (5 percent) increase in right ventricular mass and a 4.1 mL (3%) increase in right ventricular end-diastolic volume.

These relationships remained after accounting for differences among participants in cardiovascular risk factors, left ventricular mass and volume, markers of inflammation, lung disease and socioeconomic status.

The authors note that this type of study can be limited in several ways. Specifically, estimates of air pollution exposure are not perfect and it remains possible that something related to air pollution, but not air pollution itself (known as confounding), was responsible for the association. For these reasons and others, this study cannot prove that traffic-related air pollution causes changes in the right heart, but does strongly suggest the relationship.

“The morphologic changes in the right ventricle of the heart that we found with increased exposure to nitrogen dioxide add to the body of evidence supporting a connection between traffic-related air pollution and cardiovascular disease,” said Dr, Leary. “The many adverse effects of air pollution on human health support continued efforts to reduce this burden.”


Story Source:

The above story is based on materials provided by American Thoracic Society (ATS). Note: Materials may be edited for content and length.


Journal Reference:

  1. Peter J Leary, Joel D Kaufman, R Graham Barr, David A Bluemke, Cynthia L Curl, Catherine L Hough, Joao A Lima, Adam A Szpiro, Victor C Van Hee, Steven M Kawut. Traffic Related Air Pollution and the Right Ventricle: The Multi-Ethnic Study of Atherosclerosis. American Journal of Respiratory and Critical Care Medicine, 2014; 140304123758006 DOI: 10.1164/rccm.201312-2298OC

Cite This Page:

American Thoracic Society (ATS). "Traffic-related air pollution associated with changes in right ventricular structure, function." ScienceDaily. ScienceDaily, 7 March 2014. <www.sciencedaily.com/releases/2014/03/140307083704.htm>.
American Thoracic Society (ATS). (2014, March 7). Traffic-related air pollution associated with changes in right ventricular structure, function. ScienceDaily. Retrieved February 28, 2015 from www.sciencedaily.com/releases/2014/03/140307083704.htm
American Thoracic Society (ATS). "Traffic-related air pollution associated with changes in right ventricular structure, function." ScienceDaily. www.sciencedaily.com/releases/2014/03/140307083704.htm (accessed February 28, 2015).

Share This


More From ScienceDaily



More Earth & Climate News

Saturday, February 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Death Toll from Afghan Avalanches Tops 200

Death Toll from Afghan Avalanches Tops 200

AFP (Feb. 27, 2015) More than 200 people have been killed in a series of avalanches triggered by heavy snowfall in Afghanistan. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
France, Philippines Call for Agreement on Climate Change

France, Philippines Call for Agreement on Climate Change

Reuters - News Video Online (Feb. 27, 2015) The presidents of France and the Philippines issue a joint appeal for a binding agreement on climate change. Katie Sargent reports. Video provided by Reuters
Powered by NewsLook.com
The Big Melt: Antarctica's Retreating Ice

The Big Melt: Antarctica's Retreating Ice

AP (Feb. 27, 2015) From the ground in this extreme northern part of Antarctica, spectacularly white and blinding ice seems to extend forever. What can&apos;t be seen is the battle raging underfoot to re-shape Earth. Water is eating away at the Antarctic ice. (Feb. 27) Video provided by AP
Powered by NewsLook.com
Winter Storm Means Dangerous Driving in South

Winter Storm Means Dangerous Driving in South

AP (Feb. 26, 2015) A new winter storm is stretching across the south, making travel treacherous throughout the region. (Feb. 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins